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Published on: February 5, 2021
FlyBase: introduction of the Drosophila melanogaster Release 6 reference genome assembly and large-scale migration of
Gilberto dos Santos1, Andrew J Schroeder2, Joshua L Goodman3
1The Biological Laboratories, Harvard University, 16 Divinity Avenue, Cambridge, MA 02138, USA dossantos@morgan.harvard.edu.
Abstract:
Release 6, the latest reference genome assembly of the fruit fly Drosophila melanogaster, was released by the Berkeley Drosophila Genome Project in 2014; it replaces their previous Release 5 genome assembly, which had been the reference genome assembly for over 7 years. With the enormous amount of information now attached to the D. melanogaster genome in public repositories and individual laboratories, the replacement of the previous assembly by the new one is a major event requiring careful migration of annotations and genome-anchored data to the new, improved assembly. In this report, we describe the attributes of the new Release 6 reference genome assembly, the migration of FlyBase genome annotations to this new assembly, how genome features on this new assembly can be viewed in FlyBase (http://flybase.org) and how users can convert coordinates for their own data to the corresponding Release 6 coordinates.
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