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Published on: July 9, 2014
Cytomegalovirus proctitis mimicking rectal cancer in an immunocompetent elderly patient: a case report
Sathyavani Subbarao1, Anthony O'Sullivan, Tolu Adesina
1Department of Pathology, North Middlesex University Hospital, Sterling Way, N181QX London, UK. sathyavani81@gmail.com.
Background:
Cytomegalovirus infection is associated with significant morbidity and mortality in immunocompromised patients, but its impact on immunocompetent patients is still poorly understood. Furthermore, there is increasing evidence implying that chronic infection may contribute to a heightened cardiovascular risk.
Case Presentation:
We describe the case of incidental diagnosis of Cytomegalovirus proctitis in an immune-competent white British elderly gentleman, admitted following a stroke and investigated for rectal cancer following the development of bloody diarrhoea and persistent systemic inflammatory response.
Conclusion:
This raised some several interesting points; firstly that we must revise our approach to investigating the immunocompetent elderly patient, secondly, could chronic Cytomegalovirus infection have contributed to the presentation of stroke in this patient and lastly what are the existing evidence for treatment in this population? We use this opportunity to try and address some of these questions and feel that this would be of benefit to the wider audience.We discuss the risk factors for disease in immune-competent patients and also a brief overview of the benefits of treatment in this population.
Insights
Cytomegalovirus (CMV) proctitis was incidentally diagnosed in an immunocompetent elderly man. This case highlights the need to consider CMV in elderly patients presenting with gastrointestinal issues and systemic inflammation.
Area of Science:
- Infectious Diseases
- Gastroenterology
- Geriatrics
Background:
- Cytomegalovirus (CMV) infection poses significant risks for immunocompromised individuals.
- The impact of CMV on immunocompetent individuals, particularly the elderly, is less understood.
- Emerging evidence suggests a link between chronic CMV infection and increased cardiovascular risk.
Observation:
- A case of incidental Cytomegalovirus proctitis diagnosis in an immunocompetent elderly male is presented.
- The patient was admitted following a stroke and investigated for rectal cancer due to bloody diarrhea and systemic inflammation.
- This case underscores the importance of considering CMV in the differential diagnosis of elderly patients with non-specific symptoms.
Findings:
- The case prompts a re-evaluation of diagnostic approaches for immunocompetent elderly patients with gastrointestinal symptoms.
- It raises questions about the potential role of chronic CMV infection in cerebrovascular events like stroke.
- Evidence regarding the benefits of treating CMV in immunocompetent elderly patients requires further exploration.
Implications:
- Revised diagnostic strategies are needed for immunocompetent elderly patients presenting with concerning symptoms.
- The potential contribution of chronic CMV infection to cardiovascular events warrants further investigation.
- Understanding the benefits of CMV treatment in this population is crucial for clinical practice.
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