Protein kinase C in cellular transformation: a valid target for therapy?

Anuradha Tarafdar1, Alison M Michie1

  • 1*Paul O'Gorman Leukaemia Research Centre, Institute of Cancer Sciences, University of Glasgow, 21 Shelley Road, Glasgow G12 02D, U.K.

Summary

Protein Kinase C (PKC) isoforms are implicated in chronic lymphocytic leukemia (CLL) cell survival. Targeting these PKC signaling pathways linked to the B-cell receptor (BCR) may offer new therapeutic strategies for CLL.

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