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Updated: Apr 20, 2026
10:39
3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
Published on: June 2, 2014
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Episodic acute migraine treatment.
1Cleveland Clinic Headache Center, Cleveland, Ohio.
Headache
|November 18, 2014
Summary
Migraine treatment is not one-size-fits-all. While triptans and DHE are common, some patients need NSAIDs or dopamine blockers, alone or in combination, for effective migraine relief.
Area of Science:
- Neurology
- Pharmacology
Background:
- The ideal migraine medication offers rapid, complete relief for all patients, but such a treatment remains unavailable.
- Current treatments include triptans, dihydroergotamine (DHE), and nonsteroidal anti-inflammatory drugs (NSAIDs).
Purpose of the Study:
- To review the current landscape of migraine pharmacotherapy.
- To discuss alternative and adjunctive treatment strategies for migraine management.
Main Methods:
- Literature review of existing migraine treatment options.
- Analysis of treatment efficacy and patient response variability.
Main Results:
- Most patients respond to triptans or DHE.
- A subset of patients require combination therapy (triptans/DHE with NSAIDs) or NSAIDs alone.
- Dopamine blockers offer an alternative, particularly for patients with vascular disease, and can be used adjunctively.
Conclusions:
- Migraine treatment requires a personalized approach, considering individual patient needs and medical history.
- Combination therapies and alternative drug classes like dopamine blockers expand treatment options for refractory or specific patient populations.
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