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Pulmonary benign metastasizing leiomyoma: a case report
1Department of Pathology, Tongji Hospital, Tongji University School of Medicine Shanghai 200065, China.
International Journal of Clinical and Experimental Pathology
|November 18, 2014
Summary
Pulmonary benign metastasizing leiomyoma (PBML) is a rare lung tumor originating from smooth muscle. This case study highlights a patient with PBML, showing no recurrence after two years.
Area of Science:
- Oncology
- Pathology
- Pulmonology
Background:
- Pulmonary benign metastasizing leiomyoma (PBML) is a rare condition.
- It typically affects women with a history of uterine leiomyoma.
- PBML involves benign smooth muscle tumors metastasizing to the lungs.
Observation:
- A case of PBML was analyzed, focusing on clinical and pathological data.
- Chest CT revealed multiple well-defined nodules in both lung lobes.
- Tumor cells in the lung were well-differentiated and resembled the primary tumor.
Findings:
- Immunohistochemistry confirmed the smooth muscle origin, consistent with PBML.
- Estrogen and progestogen receptor positivity was noted in both primary and metastatic lesions.
- Pulmonary function remained normal, with no tumor recurrence over two years.
Implications:
- This case contributes to understanding PBML presentation and behavior.
- Hormone receptor status may be relevant for PBML management.
- Long-term observation suggests a potentially indolent course for some PBML cases.
