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Published on: December 5, 2020
Antitumor activity of monoterpenes found in essential oils
Marianna Vieira Sobral1, Aline Lira Xavier2, Tamires Cardoso Lima3
1Departamento de Ciências Farmacêuticas, Universidade Federal da Paraíba, 58051-970 João Pessoa, PB, Brazil ; Programa de Pós-Graduação em Produtos Naturais e Sintéticos Bioativos, Universidade Federal da Paraíba, Caixa Postal 5009, 58015-970 João Pessoa, PB, Brazil.
Abstract:
Cancer is a complex genetic disease that is a major public health problem worldwide, accounting for about 7 million deaths each year. Many anticancer drugs currently used clinically have been isolated from plant species or are based on such substances. Accumulating data has revealed anticancer activity in plant-derived monoterpenes. In this review the antitumor activity of 37 monoterpenes found in essential oils is discussed. Chemical structures, experimental models, and mechanisms of action for bioactive substances are presented.
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