Cooperative interactions between p53 and NFκB enhance cell plasticity

Alessandra Bisio1, Judit Zámborszky2, Sara Zaccara1

  • 1Laboratory of Transcriptional Networks, Centre for Integrative Biology, CIBIO, University of Trento, Trento, 38123, Italy.

Oncotarget
|November 18, 2014
PubMed
Summary

This study reveals a crosstalk between p53 and NFκB transcription factors in breast cancer cells, influencing cell migration and treatment response. This interaction impacts gene expression, potentially altering cancer progression and therapy effectiveness.

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