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Viral Recombination

Viral Recombination

Cells are sometimes infected by more than one virus at once. When two viruses disassemble to expose their genomes for replication in the same cell, similar regions of their genomes can pair together and exchange sequences in a process called recombination. Alternatively, viruses with segmented genomes can swap segments in a process called reassortment.

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Arbovirus Infections As Screening Tools for the Identification of Viral Immunomodulators and Host Antiviral Factors

Arbovirus Infections As Screening Tools for the Identification of Viral Immunomodulators and Host Antiviral Factors

Published on: September 13, 2018

Bunyavirus-vector interactions.

Kate McElroy Horne¹, Dana L Vanlandingham²

¹Biosecurity Research Institute, Kansas State University, Manhattan, KS 66506, USA. kmhorne@ksu.edu.

|November 18, 2014

Summary

This summary is machine-generated.

Bunyaviruses are a large viral family with many pathogens. This review explores bunyavirus-vector interactions, focusing on arthropod-borne viruses like Orthobunyavirus and Hantavirus.

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Area of Science:

Virology
Arthropod-borne diseases
Emerging infectious diseases

Background:

Bunyaviridae is a large virus family with over 350 viruses.
Several genera, including Hantavirus, Orthobunyavirus, Nairovirus, Tospovirus, and Phlebovirus, contain significant human and agricultural pathogens.
Orthobunyavirus, Nairovirus, and Phlebovirus genera are transmitted by arthropods, which also act as reservoirs.

Purpose of the Study:

To provide an overview of important emerging or re-emerging bunyaviruses.
To describe bunyavirus-vector interactions.
To synthesize current knowledge from epidemiological, ultrastructural, and genetic studies.

Main Methods:

Review of epidemiological data.
Analysis of ultrastructural studies.
Examination of genetic studies.

Main Results:

Bunyaviruses are transmitted by various hematophagous arthropods.
Arthropods serve dual roles as vectors and reservoirs for many bunyaviruses.
Emerging and re-emerging bunyaviruses pose significant threats.

Conclusions:

Bunyavirus-vector interactions are crucial for understanding virus transmission and evolution.
Further research into these interactions is essential for disease control.
This review highlights key aspects of bunyavirus-arthropod relationships.