Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Gas Chromatography: Types of Detectors-II01:19

Gas Chromatography: Types of Detectors-II

1.5K
In gas chromatography, different detectors are employed to meet specific analytical needs. These detectors are often categorized based on their detection mechanisms and the types of compounds they are best suited to analyze. Thermal Conductivity Detectors (TCD), Flame Ionization Detectors (FID), and Electron Capture Detectors (ECD) represent common categories, each with unique operating principles and applications. However, beyond these, several other detectors are designed for more specialized...
1.5K
Gas Chromatography: Overview of Detectors01:13

Gas Chromatography: Overview of Detectors

2.7K
Detectors in gas chromatography (GC) help identify and quantify the components of a mixture by translating chemical properties into measurable signals, which are displayed on a chromatogram. Detectors can be categorized into two main types: destructive and non-destructive.
A non-destructive detector allows a sample to be analyzed without altering or consuming it, meaning the sample can be collected after detection for further analysis. Examples include thermal conductivity detectors and...
2.7K
Gas Chromatography: Types of Detectors-I01:21

Gas Chromatography: Types of Detectors-I

2.3K
There are different types of detectors used in gas chromatography, each with its own specific properties that make it suitable for detecting certain types of analytes. The most commonly used detectors in GC are thermal conductivity detector (TCD), flame ionization detector (FID), and electron capture detector (ECD).
TCD is the earliest and most widely used detector that operates by measuring the changes in the thermal conductivity of the carrier gas. When a sample compound enters the detector,...
2.3K
Inductively Coupled Plasma Atomic Emission Spectroscopy: Instrumentation01:26

Inductively Coupled Plasma Atomic Emission Spectroscopy: Instrumentation

1.0K
Inductively coupled plasma (ICP) is the common plasma source used in atomic emission spectroscopy (AES), a technique that detects and analyzes various elements in a sample. This method is often called inductively coupled plasma atomic emission spectroscopy (ICP-AES).
There are three main types of inductively coupled plasma atomic emission spectroscopy  (ICP-AES) instruments: sequential, simultaneous multichannel, and Fourier transform instruments, with the latter being less commonly used....
1.0K
UV–Vis Spectrometers01:14

UV–Vis Spectrometers

4.7K
The absorbance of UV and visible (UV–visible) radiations is measured using a UV–visible spectrophotometer. Deuterium lamps, which emit UV radiation, and tungsten lamps, which produce radiation in the visible region, are used as light sources in UV–visible spectrophotometers. A monochromator or prism is used for diffraction grating, i.e., to split the incoming radiation into different wavelengths. A system of slits is used to focus the desired wavelength on the sample cell.
4.7K
Atomic Emission Spectroscopy: Lab01:29

Atomic Emission Spectroscopy: Lab

855
AES is a powerful analytical technique, especially effective when used with plasma sources, producing abundant spectra in characteristic emission lines. The Inductively Coupled Plasma (ICP), in particular, yields superior quantitative analytical data due to its high stability, low noise, low background, and minimal interferences under optimal experimental conditions. However, newer air-operated microwave sources are emerging as promising alternatives that could be more cost-effective than...
855

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Olanzapine enhances the response of PD-(L)1 inhibitor immunotherapy: A retrospective efficacy analysis in advanced malignancies.

iScience·2026
Same author

Microwave and terahertz frequencies of O2 determined with saturated absorption spectroscopy near 763 nm.

The Journal of chemical physics·2025
Same author

Cavity-Enhanced Doppler-Broadening Thermometry via All-Frequency Metrology.

Physical review letters·2025
Same author

A Patient-Centric, Open-Label, Multicenter, Phase II Study of Lorlatinib Monotherapy in the First-Line Treatment of Patients With locally Advanced or Metastatic ALK-Positive Non-Small Cell Lung Cancer (CTONG2203).

Clinical lung cancer·2025
Same author

Vibrational Analysis Based on Cavity-Enhanced Raman Spectroscopy: Cyclohexane.

The journal of physical chemistry. A·2025
Same author

Toripalimab plus chemotherapy for first line treatment of advanced non-small cell lung cancer (CHOICE-01): final OS and biomarker exploration of a randomized, double-blind, phase 3 trial.

Signal transduction and targeted therapy·2024

Related Experiment Video

Updated: Apr 20, 2026

Infrared Degenerate Four-wave Mixing with Upconversion Detection for Quantitative Gas Sensing
10:42

Infrared Degenerate Four-wave Mixing with Upconversion Detection for Quantitative Gas Sensing

Published on: March 22, 2019

6.7K

Ultrasensitive, self-calibrated cavity ring-down spectrometer for quantitative trace gas analysis.

Bing Chen, Yu R Sun, Ze-Yi Zhou

    Applied Optics
    |November 18, 2014
    PubMed
    Summary

    A new cavity ring-down spectrometer uses telecom diode lasers for precise trace gas detection. This instrument achieves high sensitivity and accuracy for analyzing gases like CO2 at very low concentrations.

    More Related Videos

    Quantitative Detection of Trace Explosive Vapors by Programmed Temperature Desorption Gas Chromatography-Electron Capture Detector
    07:57

    Quantitative Detection of Trace Explosive Vapors by Programmed Temperature Desorption Gas Chromatography-Electron Capture Detector

    Published on: July 25, 2014

    20.5K
    Quantitative Analysis by Thermogravimetry-Mass Spectrum Analysis for Reactions with Evolved Gases
    06:51

    Quantitative Analysis by Thermogravimetry-Mass Spectrum Analysis for Reactions with Evolved Gases

    Published on: October 29, 2018

    10.2K

    Related Experiment Videos

    Last Updated: Apr 20, 2026

    Infrared Degenerate Four-wave Mixing with Upconversion Detection for Quantitative Gas Sensing
    10:42

    Infrared Degenerate Four-wave Mixing with Upconversion Detection for Quantitative Gas Sensing

    Published on: March 22, 2019

    6.7K
    Quantitative Detection of Trace Explosive Vapors by Programmed Temperature Desorption Gas Chromatography-Electron Capture Detector
    07:57

    Quantitative Detection of Trace Explosive Vapors by Programmed Temperature Desorption Gas Chromatography-Electron Capture Detector

    Published on: July 25, 2014

    20.5K
    Quantitative Analysis by Thermogravimetry-Mass Spectrum Analysis for Reactions with Evolved Gases
    06:51

    Quantitative Analysis by Thermogravimetry-Mass Spectrum Analysis for Reactions with Evolved Gases

    Published on: October 29, 2018

    10.2K

    Area of Science:

    • Spectroscopy
    • Laser Technology
    • Environmental Science

    Background:

    • Cavity ring-down spectroscopy (CRDS) is a powerful technique for sensitive gas detection.
    • Existing CRDS systems often require complex active-locking mechanisms for lasers and cavities.
    • Trace gas analysis demands high precision and sensitivity for accurate measurements.

    Purpose of the Study:

    • To develop a simplified cavity ring-down spectrometer for trace gas detection.
    • To achieve high spectral calibration precision and high sensitivity without active laser or cavity locking.
    • To demonstrate the instrument's quantitative accuracy and trace detection capabilities.

    Main Methods:

    • Utilized telecom distributed feedback (DFB) diode lasers for CRDS.
    • Employed longitudinal cavity modes as frequency markers, eliminating the need for active locking.
    • Implemented a control scheme to sequentially scan laser frequencies and match cavity modes.
    • Calibrated spectra with a relative frequency precision of 0.06 MHz.

    Main Results:

    • Achieved a noise-equivalent absorption sensitivity of 4×10-11 cm-1 Hz-1/2.
    • Demonstrated a minimum detectable absorption coefficient of 5×10-12 cm-1.
    • Verified quantitative accuracy with <0.3% relative deviation for CO2 in N2 samples.
    • Successfully detected CO2 at parts-per-billion by volume (ppbv) levels.

    Conclusions:

    • The developed CRDS instrument offers a simple structure with high sensitivity and accuracy.
    • It is well-suited for quantitative trace gas analysis, including environmental monitoring.
    • The method provides precise spectral calibration and robust trace detection capabilities.