Related Experiment Video
Updated: Apr 20, 2026

Single-Port Robotic-assisted Transaxillary Breast-conserving Surgery: A Prospective, Single-arm, Non-randomized Phase IIa Clinical Trial
Published on: August 19, 2025
Comparing standard versus prosocial internet support groups for patients with breast cancer: a randomized controlled
Stephen J Lepore1, Joanne S Buzaglo2, Morton A Lieberman2
1Stephen J. Lepore, Judith R. Greener, and Adam Davey, Temple University; Joanne S. Buzaglo and Mitch Golant, Cancer Support Community, Philadelphia, PA; and Morton A. Lieberman, University of California, San Francisco, San Francisco, CA. slepore@temple.edu.
Purpose:
Internet support group (ISG) members benefit from receiving social support and, according to the helper therapy principle, by providing support to others. To test the mental health benefits of providing support to others, this trial compared the efficacy of a standard ISG (S-ISG) and an enhanced prosocial ISG (P-ISG).
Methods:
A two-armed randomized controlled trial with 1-month pretest and post-test assessments was conducted with women (N = 184) diagnosed in the past 36 months with nonmetastatic breast cancer who reported elevated anxiety or depression. Women were randomly assigned to either the S-ISG or P-ISG condition. Both conditions included six professionally facilitated live chat sessions (90-minute weekly sessions) and access to an asynchronous discussion board; P-ISG also included structured opportunities to help and encourage others.
Results:
Relative to the S-ISG, participants in the P-ISG condition exhibited more supportive behaviors (emotional, informational, and companionate support), posted more messages that were other-focused and fewer that were self-focused, and expressed less negative emotion (P < .05). Relative to the S-ISG, participants in the P-ISG condition had a higher level of depression and anxiety symptoms after the intervention (P < .05).
Conclusion:
Despite the successful manipulation of supportive behaviors, the P-ISG did not produce better mental health outcomes in distressed survivors of breast cancer relative to an S-ISG. The prosocial manipulation may have inadvertently constrained women from expressing their needs openly, and thus, they may not have had their needs fully met in the group. Helping others may not be beneficial as a treatment for distressed survivors of breast cancer.
Related Concept Videos
Self-Help Support Groups
Accessibility and Cost-Effectiveness
One of the primary strengths of self-help...
Healthcare Agencies I
Comparing the Survival Analysis of Two or More Groups
Group Therapy
Cancer Survival Analysis