An automated internet behavioral weight-loss program by physician referral: a randomized controlled trial

Area of Science:

• Obesity research
• Behavioral science
• Digital health interventions

Background:

• Overweight and obesity are significant public health concerns.
• Effective, scalable weight management strategies are needed.
• Physician referral can facilitate patient engagement in interventions.

Purpose of the Study:

• To assess weight-loss outcomes from physician referrals to a 3-month Internet-based behavioral intervention.
• To compare outcomes with an education-only control group.

Main Methods:

• 154 overweight/obese adults (BMI 25-45 kg/m²) were randomized.
• Intervention group received 3 months of Internet behavioral intervention (IBI) with videos and automated feedback.
• Control group received education-only (IDEA).
• Primary outcome: 3-month weight loss; Secondary outcomes: 6-month weight loss and behavior changes.

Main Results:

• IBI resulted in significantly greater mean weight loss at 3 months (5.5 kg vs. 1.3 kg) and 6 months (5.4 kg vs. 1.3 kg) (P < 0.001).
• Over 50% of IBI participants achieved 5% weight loss at 3 and 6 months, versus ~10% in IDEA (P < 0.001).
• IBI participants reported more frequent use of weight control strategies.

Conclusions:

• Physician referral to an IBI can lead to clinically significant weight loss.
• Over half of referred patients achieved meaningful weight reduction.
• Further research should explore broader implementation in various healthcare settings.