Majocchi's Granuloma after Topical Corticosteroids Therapy

Area of Science:

• Dermatology
• Mycology
• Infectious Diseases

Background:

• Majocchi's granuloma (MG) is an uncommon dermatophyte infection affecting deep cutaneous and subcutaneous tissues.
• Typically, dermatophytes infect superficial structures like hair, epidermis, and nails; deep tissue involvement is rare.
• MG presents in two forms: perifollicular papular (healthy individuals) and deep subcutaneous nodular (immunocompromised hosts).

Purpose of the Study:

• To describe a unique case of Majocchi's granuloma presenting on the face.
• To highlight the diagnostic difficulties associated with varied clinical presentations of MG.
• To underscore the potential role of prolonged topical corticosteroid use in the development of MG.

Main Methods:

• Case report presentation.
• Review of clinical manifestations and diagnostic approaches for Majocchi's granuloma.
• Emphasis on direct microscopical and histological examinations for diagnosis.

Main Results:

• The case involved Majocchi's granuloma occurring on the face.
• The patient had a history of prolonged topical corticosteroid treatment.
• The varied clinical presentation, including potential mimicry of other conditions, complicated diagnosis.

Conclusions:

• Majocchi's granuloma can present atypically, even on the face.
• Prolonged topical corticosteroid use may be a predisposing factor or influence the presentation of MG.
• Accurate diagnosis relies on prompt and thorough microscopical and histological evaluation.