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Updated: Jul 15, 2026

Establishment of a Clinic-based Biorepository
07:50

Establishment of a Clinic-based Biorepository

Published on: May 29, 2017

The Canadian healthy infant longitudinal development birth cohort study: biological samples and biobanking

T J Moraes1, D L Lefebvre, R Chooniedass

  • 1Physiology and Experimental Medicine Program, The Hospital for Sick Children, Toronto, ON, Canada; Department of Paediatrics, University of Toronto, Toronto, ON, Canada.

Paediatric and Perinatal Epidemiology
|November 19, 2014
PubMed

Insights

The Canadian Healthy Infant Longitudinal Development (CHILD) study investigates genetic and environmental factors in childhood allergy and asthma. This birth cohort study collects extensive data to understand these complex interactions and inform future health research.

Area of Science:

  • Pediatric Health Research
  • Environmental Epidemiology
  • Genetic Epidemiology

Background:

  • Childhood allergy and asthma are complex conditions.
  • Genetic and environmental factors are hypothesized to interact in their development.

Purpose of the Study:

  • To explore the interplay of genetic and environmental factors in childhood allergy and asthma.
  • To establish a comprehensive birth cohort for longitudinal health research.

Main Methods:

  • Longitudinal, general population birth cohort study.
  • Recruitment from mid-pregnancy to 5 years of age.
  • Collection of biological samples, questionnaires, clinical measures, and environmental data.

Main Results:

  • Recruited 3624 families.
  • Collected and archived thousands of biological samples and questionnaires.
  • Established protocols for sample and data collection, storage, and release.

Conclusions:

  • The CHILD study repository is a valuable resource for current and future research.
  • Findings will inform studies on asthma, allergy, and other infant/child health aspects.
  • Provides a wealth of data for understanding pediatric health determinants.
Abstract

Keywords:
allergyasthmabiological samplesbirth cohort

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