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Related Concept Videos

Endocarditis I: Introduction01:25

Endocarditis I: Introduction

866
Introduction:Endocarditis is the infection of the endocardium, the inner lining of the heart and its valves. When the heart muscle is involved, the condition is termed myocarditis, while an infection of the outer lining is called pericarditis. Infective endocarditis (IE) primarily affects the endocardium, where pathogens adhere to the valves or lining, forming vegetation that can lead to severe complications. Infective endocarditis occurs when microorganisms, usually bacteria from other body...
866
Endocarditis II: Clinical Features of Infective Endocarditis01:25

Endocarditis II: Clinical Features of Infective Endocarditis

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Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
907
Endocarditis III: Medical Management01:18

Endocarditis III: Medical Management

351
Infective endocarditis management involves a multifaceted approach encompassing infection prevention, lifestyle modifications, pharmacological therapy, and surgical management.Infection Prevention:Hand Hygiene: Thorough handwashing is crucial to prevent the spread of infection. Hand hygiene should be performed regularly, especially before and after using the restroom.Oral Hygiene: Good oral hygiene is essential. It includes brushing teeth immediately after waking up and before bed, flossing...
351
Mitral Stenosis I: Introduction01:22

Mitral Stenosis I: Introduction

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Mitral Valve Stenosis (MVS) is a heart condition where the mitral valve narrows, impeding blood circulation from the left atrium to the left ventricle. The etiology and pathophysiology of this condition are multifaceted, leading to a cascade of cardiovascular complications.Causes of Mitral Valve StenosisRheumatic Heart Disease: It is the main cause of mitral valve stenosis, particularly in developing nations. This condition arises from rheumatic fever, an inflammatory illness resulting from...
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Endocarditis IV: Nursing Management01:29

Endocarditis IV: Nursing Management

611
Infective endocarditis (IE) is a chronic infection of the heart's endocardium, primarily affecting the heart valves. A detailed nursing assessment for a patient with IE involves collecting subjective and objective data to ensure an accurate diagnosis and timely intervention.Subjective DataThe nurse gathers information about the patient's symptoms and complaints during the subjective assessment. Patients with infective endocarditis often report non-specific symptoms that can mimic other...
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Mitral Stenosis III: Medical Management01:26

Mitral Stenosis III: Medical Management

491
Mitral stenosis, a condition marked by the narrowing of the mitral valve, necessitates an integrated approach for effective management. This approach includes preventative measures, medical therapy, and surgical interventions to reduce symptoms and prevent complications.PreventionPrevention of mitral stenosis primarily focuses on reducing the incidence of bacterial infections, particularly streptococcal infections, which can lead to rheumatic fever and subsequent valvular damage. Timely...
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Related Experiment Video

Updated: Apr 20, 2026

An In Vitro Model of a Parallel-Plate Perfusion System to Study Bacterial Adherence to Graft Tissues
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Gemella morbillorum prosthetic aortic valve endocarditis.

Lokesh Shahani1

  • 1Department of Internal Medicine, Baylor College of Medicine, Houston, Texas, USA.

BMJ Case Reports
|November 20, 2014
PubMed
Summary

Gemella morbillorum, a common human commensal, can cause prosthetic valve endocarditis. This case highlights the importance of considering this bacterium in patients with suspected infective endocarditis.

Area of Science:

  • Microbiology
  • Cardiology
  • Infectious Diseases

Background:

  • Gemella morbillorum is a Gram-positive coccus, typically a commensal of human flora.
  • Infective endocarditis is a serious infection, particularly in patients with prosthetic heart valves.

Observation:

  • A patient with a prosthetic bovine aortic valve presented with symptoms of endocarditis, including fever and congestive heart failure.
  • Blood cultures initially suggested a viridans streptococcal species, but 16S rRNA gene sequencing identified it as Gemella morbillorum.
  • Echocardiography revealed vegetation on the prosthetic valve and a perivalvular abscess.

Findings:

  • The patient was successfully treated with a 6-week course of penicillin G and gentamicin, combined with cardiac surgery.
  • This case confirms Gemella morbillorum as a causative agent of prosthetic valve endocarditis.

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  • Bacteremia with Gemella morbillorum warrants consideration for infectious endocarditis.
  • Implications:

    • Clinicians should consider Gemella morbillorum in the differential diagnosis of infective endocarditis, especially in patients with prosthetic valves.
    • Accurate identification of bacteria, including commensals, is crucial for appropriate treatment of cardiac infections.
    • This case contributes to the understanding of Gemella morbillorum's pathogenicity in cardiovascular settings.