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Updated: Apr 20, 2026

Methods to Quantify Pharmacologically Induced Alterations in Motor Function in Human Incomplete SCI
Published on: April 18, 2011
[Jackson's theories on the nature of motor symptoms]
1Formerly at Tohoku University Graduate School of Medicine.
Abstract:
Of John Hughlings Jackson's many contributions to neurological symptomatology, three motor symptoms serve as illustrations of his greatness: convulsions beginning unilaterally with the "march of spasms" (later called Jacksonian epilepsy), tetanus-like seizures (later called Jacksonian cerebellar fits), and cerebellar attitude (later absorbed into the category of "decerebrate rigidity"). The author has summarized their clinical characteristics and the underlying pathophysiological mechanisms as originally described by Jackson. His unique theory of "amicable antagonism" between the cerebrum and the cerebellum is also discussed. This dynamic concept can be considered a forerunner of theories of "rivalry" between higher brain centers.
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