Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Nonamyloidotic fibrillary glomerulopathy.

J Neill¹, J Rubin

¹Department of Pathology, University of Mississippi Medical Center, Jackson 39216-4505.

Archives of Pathology & Laboratory Medicine

|May 1, 1989

Summary

This case study details a woman with nonamyloidotic fibrillary glomerulopathy and Down's syndrome. The rare co-occurrence of these conditions suggests no direct causal link between them.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Implementing a participant-driven water management initiative to support Maryland hospitals.

Infection prevention in practice·2026

Same author

Engineering SIRPα conformational plasticity to reveal a cryptic pocket suitable for structure-based drug design.

bioRxiv : the preprint server for biology·2026

Same author

Sensibility of the Teeth Explained on Hydrostatic Principles.

Medical examiner (Philadelphia, Pa.)·2023

Same author

The role of Kölliker-Fuse nucleus in breathing variability.

bioRxiv : the preprint server for biology·2023

Same author

Health-protective behaviour, social media usage and conspiracy belief during the COVID-19 public health emergency - CORRIGENDUM.

Psychological medicine·2021

Same author

Union of the European Phoniatricians' position statement on the exit strategy of phoniatric and laryngological services: staying safe and getting back to normal after the peak of coronavirus disease 2019 (issued on 25th May 2020).

The Journal of laryngology and otology·2020

Area of Science:

Nephrology
Genetics
Internal Medicine

Background:

Nonamyloidotic fibrillary glomerulopathy (NFG) is a rare kidney disease.
Down syndrome (DS) is a genetic disorder associated with various health complications.
Co-occurrence of NFG and DS is exceptionally uncommon.

Observation:

A 28-year-old woman presented with a ten-year history of stable renal insufficiency.
She exhibited nephrotic-range proteinuria and a diagnosis of sarcoidosis.
The patient displayed seven of the 25 characteristic physical signs of Down syndrome.

Findings:

The patient was diagnosed with nonamyloidotic fibrillary glomerulopathy.
The clinical presentation included stable chronic kidney disease and significant proteinuria.
The co-occurrence of NFG, sarcoidosis, and Down syndrome was noted.

Implications:

The rarity of this specific combination of conditions suggests they are likely independent entities.
This case highlights the importance of comprehensive evaluation in patients with multiple comorbidities.
Further research may elucidate potential, albeit rare, associations or shared risk factors.

Related Experiment Videos