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Ossifying plexiform tumor.

Solomon S Lee1, Brian L Baker, Joshua D G Gapp

  • 1Department of Pathology, University of Tennessee Graduate School of Medicine, Knoxville, TN, USA.

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Summary
This summary is machine-generated.

This case report details a rare ossifying plexiform tumor in a 64-year-old female

Keywords:
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Area of Science:

  • Orthopedic Oncology
  • Skeletal Pathology
  • Soft Tissue Tumors

Background:

  • Ossifying plexiform tumor is an exceedingly rare neoplasm.
  • This report details a unique case in a 64-year-old female, contributing to the limited literature.

Observation:

  • A 64-year-old female presented with a 2-year history of a hardening, painful nodule on her right thumb.
  • Physical examination revealed a tender, mobile 2-cm subcutaneous nodule.
  • Radiography showed stippled calcification without phalangeal involvement.

Findings:

  • Histopathological analysis demonstrated a well-delineated tumor with epithelioid and spindled cells in a plexiform pattern, featuring bone formation.
  • Neoplastic cells exhibited mild nuclear pleomorphism without necrosis or mitoses.
  • Benign features were noted in osteocytes and osteoblasts within bone islands.

Implications:

  • Complete local excision resulted in a tumor-free status for 1 year post-operation.
  • Ossifying plexiform tumors appear to be benign, with no reported instances of metastasis or progression.
  • This case reinforces the typical presentation of these rare tumors on the digits of female patients.