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Are we accurately predicting bladder capacity in infants?

Daniel F G Costa1, Luke T Lavallée1, Claude Dubois1

  • 1Department of Surgery, Division of Pediatric Urology, Children's Hospital of Eastern Ontario, University of Ottawa, Ottawa, ON.

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Summary

Normal bladder capacity in infants under 1 year old is approximately 48.9 mL. This finding highlights the need for new methods to estimate infant bladder capacity, as current formulas are inaccurate.

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Area of Science:

  • Pediatric Urology
  • Infant Health
  • Urodynamics

Background:

  • Estimating bladder capacity is crucial for diagnosing urological disorders.
  • Established reference ranges exist for adults and older children, but not for infants.
  • Accurate infant bladder capacity data is needed for clinical evaluation.

Purpose of the Study:

  • To determine the normal bladder capacity in infants less than 1 year of age.
  • To establish validated reference ranges for infant bladder capacity.
  • To compare infant bladder capacity with existing predictive formulas.

Main Methods:

  • Retrospective chart review of infants (0-12 months) with spinal dysraphism stigmata.
  • Inclusion of patients with normal urologic assessment and no surgery.
  • Urodynamic studies performed using UDS-600 with standardized bladder filling rate.
  • Bladder capacity defined as volume at spontaneous voiding around catheter.

Main Results:

  • 84 out of 183 (46%) patients met inclusion criteria.
  • Median age of infants was 9.0 months.
  • Average bladder capacity was 48.9 mL (SD 32.8).
  • Mean detrusor pressure at capacity was 8.5 cmH2O (SD 10.0).

Conclusions:

  • Infant bladder capacity (median age 9.0 months) averages 48.9 mL.
  • This volume is significantly less than predicted by common formulas.
  • A novel method for estimating infant bladder capacity is necessary.