Related Experiment Video

Updated: Apr 20, 2026

Chromatin Immunoprecipitation ChIP in Mouse T-cell Lines
11:39

Chromatin Immunoprecipitation ChIP in Mouse T-cell Lines

Published on: June 17, 2017

19.0K

Using mouse models to study function of transcriptional factors in T cell development

Peng Li1, Yiren Xiao1, Zhixin Liu1

  • 1Key Laboratory of Regenerative Biology, Guangzchou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China ; Guangdong Provincial Key Laboratory of Stem Cell and Regenerative Medicine, Guangzhou, China.

Cell Regeneration (London, England)
|November 20, 2014
PubMed

Keywords:
Bcl11bGenetic modified miceHumanized miceLymphopoiesisT cell development

More Related Videos

Retroviral Transduction of T-cell Receptors in Mouse T-cells10:14

Retroviral Transduction of T-cell Receptors in Mouse T-cells

Published on: October 22, 2010

36.4K
Transnuclear Mice with Pre-defined T Cell Receptor Specificities Against Toxoplasma gondii Obtained Via SCNT13:36

Transnuclear Mice with Pre-defined T Cell Receptor Specificities Against Toxoplasma gondii Obtained Via SCNT

Published on: September 30, 2010

14.7K

Related Concept Videos

Mouse Models of Cancer Study02:43

Mouse Models of Cancer Study

Mice have long served as models for studying human biology and pathology because of their phylogenetic and physiological similarity with humans. They are also easy to maintain and breed in the laboratory, and hence, many inbred strains are now available for research. Studies on mice have contributed immeasurably to our understanding of cancer biology.
The development of transgenic, knockout, and knock-in mice has led to an exponential increase in their use as model organisms in research,...
6.8K
Mouse Models of Cancer Study02:43

Mouse Models of Cancer Study

2.6K
Master Transcription Regulators02:23

Master Transcription Regulators

Master transcription regulators are regulatory proteins that are predominantly responsible for regulating the expression of multiple genes. Often these genes work in concert to drive a  complex process. Activation of a master transcription regulator can lead to a cascade of transcriptional activation necessary for that outcome. These regulators can directly bind to the regulatory sequences of the various genes involved, or they can indirectly regulate transcription by binding to regulatory...
8.1K
General Transcription Factors01:30

General Transcription Factors

Tissue-specific transcription factors contribute to diverse cellular functions in mammals. For example, the gene for beta globin, a major component of hemoglobin, is present in all cells of the body. However, it is only expressed in red blood cells because the transcription factors that can bind to the promoter sequences of the beta globin gene are only expressed in these cells. Tissue-specific transcription factors also ensure that mutations in these factors may impair only the function of...
7.8K