Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Stem Cell Culture01:17

Stem Cell Culture

6.7K
Stem cell research aims to find ways to use stem cells to regenerate and repair cellular damage. Over time, most adult cells undergo the wear and tear of aging and lose their ability to divide and repair themselves. Stem cells do not display a particular morphology or function. Adult stem cells, which exist as a small subset of cells in most tissues, keep dividing and can differentiate into a number of specialized cells generally formed by that tissue. These cells enable the body to renew and...
6.7K
Source And Potency Of Stem Cells01:27

Source And Potency Of Stem Cells

6.9K
Stem cells are undifferentiated cells with extensive self-renewal properties that help them maintain their population during the fetal and adult stages of life. They can specialize in all cell types of the human body. However, their differential potential may vary and can be classified into five types. Stem cells can be (1) Totipotent, (2) Pluripotent, (3) Multipotent, (4) Oligopotent, and (5) Unipotent. Each stem cell has a specific origin; the fertilized egg or zygote is a totipotent cell and...
6.9K
Stem Cell Therapy for Tissue Regeneration01:21

Stem Cell Therapy for Tissue Regeneration

5.0K
Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
Types of Stem Cells used in Stem Cell Therapy
The two main cell...
5.0K
Induced Pluripotent Stem Cells01:06

Induced Pluripotent Stem Cells

6.4K
Stem cells are undifferentiated cells that divide and produce different cell types. Ordinarily, cells that have differentiated into a specific cell type are terminally differentiated; however, scientists have found a way to reprogram these mature cells so that they dedifferentiate and return to an unspecialized, proliferative state. These cells are pluripotent like embryonic stem cells—able to produce all cell types—and are called induced pluripotent stem cells (iPSCs).
Somatic...
6.4K
Embryonic Stem Cells00:58

Embryonic Stem Cells

33.6K
Embryonic stem (ES) cells are undifferentiated pluripotent cells, meaning they can produce any cell type in the body. This gives them tremendous potential in science and medicine since they can generate specific cell types for use in research or to replace body cells lost due to damage or disease.
33.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Posterior capsule rupture with complete lens dislocation into the vitreous cavity caused by blunt trauma: a case report.

Frontiers in medicine·2026
Same author

Epitranscriptomic m6A reader HNRNPC amplifies oxidative stress-autophagy dysregulation and aggravates placental dysfunction in preeclampsia.

Scientific reports·2026
Same author

Post-traumatic growth experience of the family members of patients admitted to the trauma intensive care unit: A phenomenological study.

Australian critical care : official journal of the Confederation of Australian Critical Care Nurses·2026
Same author

Cepharanthine triggers immunogenic cell death in solid tumors by suppressing protein kinase C zeta-mediated poly(ADP-ribose) polymerase 1 expression and synergizes with immunotherapy.

Phytomedicine : international journal of phytotherapy and phytopharmacology·2026
Same author

A head-to-head comparison of MRI and CT using Node-RADS for rectal cancer lymph nodes: Observer agreement and diagnostic performance.

European journal of radiology open·2026
Same author

Plasma-Activated Water as a Novel Irrigation Strategy for Seawater-Immersed Burn Wounds: Antibacterial Activity and Healing Promotion in Rats.

Biomedicines·2026

Related Experiment Video

Updated: Apr 20, 2026

A Simplified Method for Generating Kidney Organoids from Human Pluripotent Stem Cells
07:39

A Simplified Method for Generating Kidney Organoids from Human Pluripotent Stem Cells

Published on: April 13, 2021

7.0K

Generation of functional organs from stem cells.

Yunying Liu1, Ru Yang2, Zuping He2

  • 1State Key Laboratory of Oncogenes and Related Genes, Stem Cell Research Center, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China ; Med-X Research Institute, Shanghai Jiaotong University, Shanghai, 200127 China.

Cell Regeneration (London, England)
|November 20, 2014
PubMed
Summary

Stem cell therapy offers hope for treating diseases and repairing tissues. Generating transplantable organs using stem cells is a promising solution to donor organ shortages.

Keywords:
Blastocyst complementationDecellularizationFunctional organsRecellularizationStem cellsTissue engineering

More Related Videos

Robust Generation of Hepatocyte-like Cells from Human Embryonic Stem Cell Populations
05:49

Robust Generation of Hepatocyte-like Cells from Human Embryonic Stem Cell Populations

Published on: October 26, 2011

48.5K
Author Spotlight: Optimizing iPSC Differentiation for Efficient Production to Generate Kidney Organoids
07:22

Author Spotlight: Optimizing iPSC Differentiation for Efficient Production to Generate Kidney Organoids

Published on: September 1, 2023

4.0K

Related Experiment Videos

Last Updated: Apr 20, 2026

A Simplified Method for Generating Kidney Organoids from Human Pluripotent Stem Cells
07:39

A Simplified Method for Generating Kidney Organoids from Human Pluripotent Stem Cells

Published on: April 13, 2021

7.0K
Robust Generation of Hepatocyte-like Cells from Human Embryonic Stem Cell Populations
05:49

Robust Generation of Hepatocyte-like Cells from Human Embryonic Stem Cell Populations

Published on: October 26, 2011

48.5K
Author Spotlight: Optimizing iPSC Differentiation for Efficient Production to Generate Kidney Organoids
07:22

Author Spotlight: Optimizing iPSC Differentiation for Efficient Production to Generate Kidney Organoids

Published on: September 1, 2023

4.0K

Area of Science:

  • Regenerative Medicine
  • Stem Cell Biology
  • Organ Transplantation

Background:

  • Stem cell therapy shows potential for treating numerous diseases, including neurological disorders, heart conditions, and diabetes.
  • Tissue repair through stem cell transplantation is a recognized approach, mirroring successful organ transplants for organ failure.
  • A significant challenge in organ transplantation is the limited availability of donor organs.

Purpose of the Study:

  • To review recent advancements in generating transplantable organs using stem cells.
  • To explore various methodologies for stem cell-based organ generation.
  • To highlight the potential of stem cell-derived organs for addressing organ scarcity.

Main Methods:

  • Review of current literature on stem cell-based organogenesis.
  • Analysis of methods including single adult tissue stem cells, blastocyst complementation, and tissue engineering.
  • Examination of tissue decellularization and recellularization techniques.

Main Results:

  • Stem cells offer a viable alternative to traditional organ transplantation.
  • Multiple strategies are being developed for in vitro and in vivo organ generation.
  • Progress has been made in utilizing stem cells for tissue repair and organ replacement.

Conclusions:

  • Stem cell-based organ generation is a critical area of research for regenerative medicine.
  • Overcoming donor organ shortages may be achievable through engineered organs.
  • Further research is essential to translate these advancements into clinical practice.