Related Experiment Video
Updated: Apr 20, 2026

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery
Published on: July 5, 2021
Isolated optic nerve, chiasm, and tract involvement in Bing-Neel Syndrome.
Michael S Hughes1, Edward J Atkins, Dean M Cestari
1Harvard University (MSH); University of Saskatchewan (EJA); Massachusetts Eye and Ear Infirmary (DMC, RCS); and Massachusetts General Hospital (FH), Boston, Massachusetts.
Bing-Neel Syndrome, a central nervous system infiltration of Waldenström's macroglobulinemia, can affect vision. This study details two cases of isolated anterior visual pathway involvement, suggesting infiltrative and autoimmune mechanisms contribute to visual failure.
Area of Science:
- Neurology
- Ophthalmology
- Hematology
Background:
- Waldenström's macroglobulinemia is a rare lymphoproliferative disorder.
- Bing-Neel Syndrome (BNS) is defined as central nervous system (CNS) infiltration by Waldenström's macroglobulinemia.
- Isolated CNS involvement can present with diverse neurological and ophthalmological symptoms.
More Related Videos
13:26Measuring Connectivity in the Primary Visual Pathway in Human Albinism Using Diffusion Tensor Imaging and Tractography
Published on: August 11, 2016
13:12Partial Optic Nerve Transection in Rats: A Model Established with a New Operative Approach to Assess Secondary Degeneration of Retinal Ganglion Cells
Published on: October 15, 2017
Related Concept Videos
Cranial Nerves: Types Part I
Olfactory Nerve (Cranial Nerve I)
The olfactory nerve, or cranial nerve I, is unique as it is purely sensory and dedicated to the sense of smell. This nerve originates in the olfactory epithelium of the...
Anatomy of the Eyeball