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Updated: Apr 20, 2026

Author Spotlight: Advancing Research on Candida albicans Biofilm-Associated Prosthetic Joint Infections
Published on: February 2, 2024
Periprosthetic joint infection: modern aspects of prevention, diagnosis, and treatment
Rachel M Frank1, Michael B Cross2, Craig J Della Valle1
1Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, Illinois.
Abstract:
Periprosthetic joint infection (PJI) following total joint arthroplasty (TJA) is a devastating complication. Despite improvements in our understanding of PJI, the prevalence of this complication has not decreased in recent years, with various authors reporting rates of 1 to 2% after primary TJA and up to 7% following revision TJA. While the volume of publications, symposiums, and presentations on PJI is vast, controversy still remains regarding the prevention, diagnosis, and treatment of patients with PJI. The purpose of this article is to provide a succinct summary of the recent literature on the diagnosis, treatment, and prevention of a PJI after TJA.
Insights
Periprosthetic joint infection (PJI) after total joint arthroplasty (TJA) remains a significant challenge. This review summarizes recent literature on PJI diagnosis, treatment, and prevention strategies to improve patient outcomes.
Area of Science:
- Orthopedic Surgery
- Infectious Diseases
- Biomedical Engineering
Background:
- Periprosthetic joint infection (PJI) is a severe complication following total joint arthroplasty (TJA).
- PJI rates range from 1-2% after primary TJA to 7% after revision TJA.
- Despite extensive research, controversies persist regarding PJI prevention, diagnosis, and treatment.
Purpose of the Study:
- To provide a concise summary of recent literature on PJI.
- To address current controversies in PJI management.
- To offer insights into diagnosis, treatment, and prevention strategies for PJI after TJA.
Main Methods:
- Literature review of recent publications on PJI.
- Synthesis of current evidence on diagnosis, treatment, and prevention.
- Analysis of controversies and consensus in PJI management.
Main Results:
- Recent literature highlights ongoing challenges in reducing PJI incidence.
- Diagnostic criteria and treatment protocols for PJI continue to evolve.
- Preventive measures show variable efficacy, requiring further investigation.
Conclusions:
- Effective PJI management requires a multidisciplinary approach.
- Standardized diagnostic and treatment guidelines are crucial for optimal outcomes.
- Continued research is essential to refine PJI prevention and treatment strategies.
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