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Updated: Apr 20, 2026

Self-Assembly of Microtubule Tactoids
Published on: June 23, 2022
Field-induced assembly of colloidal ellipsoids into well-defined microtubules
Jérôme J Crassous1, Adriana M Mihut1, Erik Wernersson1
1Physical Chemistry, Department of Chemistry, Lund University, SE-22100 Lund, Sweden.
Abstract:
Current theoretical attempts to understand the reversible formation of stable microtubules and virus shells are generally based on shape-specific building blocks or monomers, where the local curvature of the resulting structure is explicitly built-in via the monomer geometry. Here we demonstrate that even simple ellipsoidal colloids can reversibly self-assemble into regular tubular structures when subjected to an alternating electric field. Supported by model calculations, we discuss the combined effects of anisotropic shape and field-induced dipolar interactions on the reversible formation of self-assembled structures. Our observations show that the formation of tubular structures through self-assembly requires much less geometrical and interaction specificity than previously thought, and advance our current understanding of the minimal requirements for self-assembly into regular virus-like structures.
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