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Updated: Apr 20, 2026
06:53
Cell Population Analyses During Skin Carcinogenesis
Published on: August 21, 2013
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Basal cell carcinoma incompletely excised: a case-control study on recurrence.
Alessandro Borghi1, Monica Corazza, Michela Ricci
1Unit of Dermatology and Infectious Diseases, Department of Medical Sciences, University of Ferrara, Ferrara, Italy - alessandro.borghi@unife.it.
Summary
For incompletely excised basal cell carcinoma (BCC), clinical observation shows similar recurrence rates to complete excision. Patient adherence to follow-up visits is crucial for managing new or recurrent BCC.
Area of Science:
- Dermatology
- Oncology
- Surgical Pathology
Background:
- Management of incompletely excised basal cell carcinoma (BCC) lacks consensus, with options including re-excision or observation.
- This study addresses the uncertainty surrounding the optimal management strategy for BCC.
- Investigating recurrence rates provides evidence for clinical decision-making.
Purpose of the Study:
- To compare recurrence rates between incompletely excised (non-re-excised) and completely excised BCCs.
- To identify factors associated with BCC recurrence.
- To inform the most appropriate care strategy for incompletely excised BCCs.
Main Methods:
- A case-control study design was employed.
- The study included a cohort of 39 incompletely excised and 107 completely excised BCCs.
- Patients were recalled for follow-up visits.
Main Results:
- Recurrence rates were 8% for incompletely excised BCCs and 3% for completely excised BCCs, with no significant difference.
- Advanced age and chronic sun exposure were linked to BCC recurrence.
- Thirty-seven percent of patients developed new BCCs, and non-adherence to follow-up was associated with a higher rate of new or recurrent BCC diagnoses.
Conclusions:
- Long-term clinical observation is a viable option for incompletely excised BCCs, particularly when re-excision is contraindicated.
- Poor patient adherence to follow-up poses a significant challenge in managing BCC.
- Effective patient follow-up strategies are essential for monitoring and managing BCC.
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