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Partial gastric pull-up in the treatment of patients with long-gap esophageal atresia
Marc Reismann1, Tina Granholm, Henrik Ehrén
1Department of Pediatric Surgery and Urology, Astrid Lindgren Children's Hospital, Karolinska University Hospital, Stockholm, Sweden, marc.reismann@gmx.de.
Insights
Partial gastric pull-up (PGP) for long-gap esophageal atresia (LGEA) shows a high complication rate, including stenosis and reflux. Current evidence suggests PGP is not recommended as an alternative treatment for LGEA.
Area of Science:
- Pediatric Surgery
- Gastroenterology
- Thoracic Surgery
Background:
- Long-gap esophageal atresia (LGEA) presents significant surgical challenges.
- Partial gastric pull-up (PGP) is a surgical technique considered for LGEA treatment.
Purpose of the Study:
- To analyze the outcomes of pediatric patients treated with PGP for LGEA.
- To evaluate the complications and long-term results associated with PGP in LGEA management.
Main Methods:
- Retrospective review of medical records for children undergoing PGP for LGEA between 1999 and 2012.
- Assessment of preoperative data, postoperative course, complications, nutritional status, and follow-up diagnostics.
Main Results:
- Nine children with LGEA treated with PGP were followed for a mean of 6.2 years.
- Early complications included leakage (n=3), while late complications were stenosis (n=7) and gastro-esophageal reflux (n=5).
- Despite good general status, the high complication rate led to the conclusion that PGP is not currently recommended for LGEA.
Conclusions:
- Partial gastric pull-up (PGP) is associated with a high rate of complications in treating long-gap esophageal atresia (LGEA).
- Stenosis and gastro-esophageal reflux are significant late complications observed after PGP.
- Further comparative studies are needed to definitively assess PGP as an alternative treatment for LGEA.
Background:
This study was to analyze outcomes of long-gap esophageal atresia (LGEA) treated with partial gastric pull-up (PGP) into the thorax.
Methods:
The medical records of all children who had undergone PGP for LGEA from 1999 to 2012 were reviewed. Preoperative data, initial postoperative course, complications, time to full oral nutrition, follow-up diagnostics and nutritional status were assessed.
Results:
Nine children who had undergone PGP were followed up for a mean period of 6.2 ± 3.1 years. Their median gestational age was 37 ± 2 weeks, and mean birth weight 2462 ± 658 g. Eight children were primarily treated with a gastrostomy, their mean age at PGP was 11.4 ± 10.9 weeks and mean weight was 4484 ± 1966 g. Their mean operation time was 199 ± 51 minutes. Leakage was an early postoperative complication in three children, one of whom had a consecutive stricture resection. Late complications were stenosis (n=7) and gastro-esophageal reflux (n=5). The general status of the children was judged as "good" or "very good" on the last presentation. The median percentile of the body-mass-index was 25. Gastroscopy at 3.7 ± 3.2 years after the operation revealed a grade I esophagitis in two children. There was no death in this group of children.
Conclusions:
Because of its high complication rate, partial gastric pull-up cannot be recommended as an alternative for the treatment of LGEA at present. A final judgment could be made on the basis of a comparative study.
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