Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

In situ three-dimensional printing for reparative and regenerative therapy.

Biomedical microdevices·2019
Same author

A Perspective on 3D Bioprinting in Tissue Regeneration.

Bio-design and manufacturing·2019
Same author

Sutureless repair of corneal injuries using naturally derived bioadhesive hydrogels.

Science advances·2019
Same author

Hierarchically Patterned Polydopamine-Containing Membranes for Periodontal Tissue Engineering.

ACS nano·2019
Same author

A Microfabricated Sandwiching Assay for Nanoliter and High-Throughput Biomarker Screening.

Small (Weinheim an der Bergstrasse, Germany)·2019
Same author

A simple layer-stacking technique to generate biomolecular and mechanical gradients in photocrosslinkable hydrogels.

Biofabrication·2019

Related Experiment Video

Updated: Apr 20, 2026

Engineering Fibrin-based Tissue Constructs from Myofibroblasts and Application of Constraints and Strain to Induce Cell and Collagen Reorganization
12:13

Engineering Fibrin-based Tissue Constructs from Myofibroblasts and Application of Constraints and Strain to Induce Cell and Collagen Reorganization

Published on: October 28, 2013

11.4K

Composite Living Fibers for Creating Tissue Constructs Using Textile Techniques.

Mohsen Akbari1, Ali Tamayol1, Veronique Laforte1

  • 1McGill University and Genome Quebec Innovation Centre, McGill University, Montreal, Quebec, H3A 0G1, Canada.

Advanced Functional Materials
|November 21, 2014
PubMed
Summary
This summary is machine-generated.

Researchers developed composite living fibers (CLFs) for tissue engineering. These cell-laden fibers integrate textile manufacturing, enabling controlled 3D construct fabrication with preserved cell viability.

More Related Videos

Hollow Fiber Bioreactors for In Vivo-like Mammalian Tissue Culture
08:28

Hollow Fiber Bioreactors for In Vivo-like Mammalian Tissue Culture

Published on: May 26, 2016

17.2K
Production of Nanofibrillar Patterned Collagen for Tissue Engineering
07:34

Production of Nanofibrillar Patterned Collagen for Tissue Engineering

Published on: September 20, 2024

1.1K

Related Experiment Videos

Last Updated: Apr 20, 2026

Engineering Fibrin-based Tissue Constructs from Myofibroblasts and Application of Constraints and Strain to Induce Cell and Collagen Reorganization
12:13

Engineering Fibrin-based Tissue Constructs from Myofibroblasts and Application of Constraints and Strain to Induce Cell and Collagen Reorganization

Published on: October 28, 2013

11.4K
Hollow Fiber Bioreactors for In Vivo-like Mammalian Tissue Culture
08:28

Hollow Fiber Bioreactors for In Vivo-like Mammalian Tissue Culture

Published on: May 26, 2016

17.2K
Production of Nanofibrillar Patterned Collagen for Tissue Engineering
07:34

Production of Nanofibrillar Patterned Collagen for Tissue Engineering

Published on: September 20, 2024

1.1K

Area of Science:

  • Biomaterials Engineering
  • Tissue Engineering
  • Textile Science

Background:

  • Precise control over cell distribution and anisotropic mechanical properties is crucial for engineered tissues.
  • Automated textile technologies offer simultaneous control over fabric patterns and directional mechanics.
  • Existing methods lack cell-laden fibers robust enough for textile assembly processes.

Purpose of the Study:

  • To introduce composite living fibers (CLFs) for fabricating cell-laden 3D tissue constructs.
  • To demonstrate the compatibility of CLFs with standard textile manufacturing techniques.
  • To ensure cellular viability and function are maintained throughout the fabrication process.

Main Methods:

  • Development of CLFs with a load-bearing synthetic polymer core coated in a cell-laden hydrogel layer.
  • Sequential drawing of the core thread through prepolymer and crosslinking reagent reservoirs.
  • Fabrication of CLFs using textile processes: weaving, knitting, braiding, winding, and embroidering.

Main Results:

  • Hydrogel layer thickness was found to increase linearly with drawing speed and prepolymer viscosity.
  • CLFs were successfully fabricated and assembled into complex 3D structures using various textile methods.
  • Cellular viability and metabolic activity remained high after CLF fabrication and assembly.

Conclusions:

  • CLFs provide a viable platform for creating anisotropic, cell-laden tissue constructs.
  • Textile manufacturing techniques can be adapted for the precise assembly of living materials.
  • This approach facilitates the engineering of functional 3D tissue constructs with integrated cellular components.