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Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
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Rheumatic heart disease or RHD is a chronic condition that results from rheumatic fever, causing permanent damage to the heart valves.Etiology and Risk FactorsIt primarily arises from rheumatic fever, an inflammatory disease that can develop after untreated or inadequately treated group A streptococcal (GAS) pharyngitis. Streptococcus spreads through direct contact with oral or respiratory secretions. While the bacteria are the causative agents, factors like malnutrition, overcrowding, poor...
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The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...
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The meaning of illness is individualized to each person who experiences an alteration in health. In contrast, disease is a medical term indicating a pathological change in the structure and function of the body or mind. It is a condition that has specific symptoms and boundaries.
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Recurrent Herpetic Stromal Keratitis in Mice, a Model for Studying Human HSK
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Relapsing pityriasis rosea.

Francesco Drago1, Giulia Ciccarese, Alfredo Rebora

  • 1Section of Dermatology, Department of Health Sciences, IRCCS Azienda Ospedaliera Universitaria San Martino - IST, Genoa, Italy.

Dermatology (Basel, Switzerland)
|November 22, 2014
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Summary
This summary is machine-generated.

Pityriasis rosea (PR) relapses are uncommon, affecting 3.7% of patients. Recurrences typically occur within a year, with milder symptoms and shorter duration than the initial outbreak.

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Area of Science:

  • Dermatology
  • Epidemiology

Background:

  • Pityriasis rosea (PR) is an acute, self-limiting skin condition.
  • The frequency and characteristics of PR relapses are not well-documented.

Purpose of the Study:

  • To determine the prevalence of pityriasis rosea relapses.
  • To characterize the clinical features and timing of PR recurrences.

Main Methods:

  • Retrospective cohort study of pityriasis rosea cases diagnosed in Genoa from 2000-2013.
  • Follow-up of 570 patients to assess relapse occurrence and features.

Main Results:

  • 21 out of 570 patients (3.7%) experienced pityriasis rosea relapses.
  • Relapses usually occurred within one year, with reduced lesion size, number, and duration, and absent herald patch.
  • Relapsing patients were predominantly male, with a mean age of 20.3 years.

Conclusions:

  • Pityriasis rosea relapses are infrequent but can occur.
  • Recurrences exhibit distinct clinical features compared to primary episodes.
  • The study suggests a potential link between PR and human herpesviruses, similar to other reactivating viruses.