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Updated: Apr 20, 2026

A Within-Subject Experimental Design using an Object Location Task in Rats
Published on: May 6, 2021
Within-subjects assessment of the within-compound associations resulting from intermixed and blocked preexposure
Gabriel Rodríguez1, Gumersinda Alonso
1Universidad del País Vasco (UPV-EHU), San Sebastián, Spain, gabriel.rodriguez@ehu.es.
Abstract:
Nonhungry rats received training consisting of intermixed presentations of a compound flavor and an element of that compound (AX, X, AX, X, . . .), and then a separate block of presentations of another compound (BX, BX, BX, . . .). Stimuli A and B were two odor solutions (almond and vanilla), and stimulus X was a highly concentrated solution of sucrose. After training, a state of hunger was induced in the rats, and their consumption levels of A and B alone were tested. We found higher test consumption of B than of A (Exp. 1). We interpreted these differences as indicating that the B-X association had become stronger than the A-X association as a result of the training. In Experiment 2, we demonstrated that the presence of X during training was necessary for that effect to appear (Exp. 2). These results give support to the recent proposal that within-compound associations are maintained better by blocked than by intermixed preexposure (Rodríguez & Alonso, 2014). We discuss the implications of this difference for explaining the intermixed-blocked perceptual-learning effect.
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