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Asymmetric breast tissue.

D B Kopans1, C A Swann, G White

  • 1Department of Radiology, Massachusetts General Hospital, Boston.

Radiology
|June 1, 1989
PubMed
Summary

Asymmetric breast tissue on mammograms is often a normal variation. Concern is warranted only if the asymmetry is palpable or shows mass, microcalcifications, or architectural distortion.

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Area of Science:

  • Radiology
  • Oncology
  • Breast Imaging

Background:

  • Asymmetric breast tissue is a common mammographic finding.
  • Its clinical significance, particularly when lacking mass or microcalcifications, requires evaluation.

Purpose of the Study:

  • To assess the significance of various forms of asymmetric breast tissue on mammograms.
  • To determine if specific types of asymmetry warrant further investigation.

Main Methods:

  • Prospective study of 8,408 mammograms.
  • Identification of 221 cases (3%) with asymmetric breast tissue.
  • Follow-up of 36-42 months, correlating mammographic findings with clinical data and biopsies.

Main Results:

  • None of the 221 patients underwent biopsy solely based on mammographic findings.
  • Three malignancies (2 breast cancers, 1 lymphoma) were diagnosed, all associated with palpable abnormalities.
  • The remaining 201 patients with asymmetric breast tissue without mass, microcalcifications, or architectural distortion had benign biopsy results or no biopsy.

Conclusions:

  • Asymmetric breast tissue without concerning features (mass, microcalcifications, architectural distortion) is often a benign finding.
  • Palpable asymmetry associated with mammographic findings increases the likelihood of malignancy.
  • Careful correlation of mammographic and clinical findings is crucial for evaluating asymmetric breast tissue.

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