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The effect of exercise on lipid profiles and inflammatory markers in lean male adolescents: a prospective
Chun-Jui Huang1, Chin-Fai Kwok, Chung-Hsing Chou
1From the *Division of Endocrinology and Metabolism, Department of Medicine, Taipei Veterans General Hospital; †Department of Medicine, National Yang-Ming University; ‡Department of Neurology, Tri-Service General Hospital; §School of Public Health, National Defense Medical Center; ∥Department of Medical Research, Taipei Veterans General Hospital; and ¶Division of Endocrinology and Metabolism, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.
Background:
Physical activity improves body composition and inflammatory markers in obese individuals, but little is known about the nonobese population.
Objective:
The aim of this study was to investigate associations between exercise and inflammatory cytokines in lean male adolescents in Taiwan.
Methods:
This interventional study enrolled a total of 79 normal body weight male adolescents [mean age, 16.8 (1.0) years] from the Army Academy of Taiwan. Body composition and inflammatory markers were measured at baseline and upon completion of a 12-week exercise intervention program.
Results:
Subjects' postintervention anthropometric measures, including waist circumference [74.6 (5.2)→72.6 (5.2) cm], hip circumference [92.3 (4.1)→89.9 (5.0) cm], body fat mass [10.2 (3.2)→8.2 (3.2) kg], and body fat percentage [15.8% (4.2)→12.6 (4.5)%] declined significantly compared to preintervention (all P<0.001), as did systolic blood pressure (P=0.002) and mean blood pressure (P = 0.020). Postintervention body height and free fat mass increased significantly (both P<0.001). Subjects' postintervention lipids including total cholesterol, low-density lipoprotein, high-density lipoprotein, and triglycerides increased significantly (all P<0.001). Inflammatory markers including adiponectin [14.32 (6.68)→31.31 (30.53) μg/mL, P<0.001], interleukin 6 [2.15 (4.81)→2.86 (6.37) pg/mL, P=0.005], and C-reactive protein [1.00 (2.57)→2.30 (4.17) μg/mL, P<0.001] increased significantly postintervention, but not leptin.
Conclusions:
Exercise training significantly improves body composition and anti-inflammatory adiponectin levels in lean male adolescents.
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