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Visual detection of Ca(2+) based on aggregation-induced emission of Au(I)-Cys complexes with superb selectivity
Yahui Guo1, Xiaoyan Tong, Liya Ji
1Key Laboratory of Analytical Chemistry for Biology and Medicine (Ministry of Education), College of Chemistry & Molecular Sciences, Wuhan University, Wuhan, 430072 China.
Abstract:
A label-free optical probe was developed for Ca(2+) detection based on the aggregation-induced emission property of Au(i)-thiolate complexes. Upon incubation with Ca(2+), the Au(I)-cysteine complexes rapidly aggregated through Cys-Ca(2+) interaction, resulting in a luminescent emission of the complexes. The label-free probe was low cost, simple in design and fast in response.

