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Comorbidity of headache and functional constipation in children: a cross-sectional survey
Soror Inaloo1, Seyyed Mohsen Dehghani, Seyyed Mohammad Hashemi
1Neuroscience Research Centers, Shiraz University of Medical Sciences, Shiraz, Islamic Republic of Iran. meshkat_114@yahoo.com.
Insights
Headache is significantly more common in children with chronic functional constipation. This study highlights a strong link between these conditions, suggesting potential impacts on emotional well-being.
Area of Science:
- Pediatric Gastroenterology
- Pediatric Neurology
Background:
- Constipation and headache are common childhood conditions.
- Previous research linked upper GI issues with headaches, but lower GI issues like constipation remained unexplored.
- This study addresses the gap by investigating the association between chronic functional constipation and headache in children.
Purpose of the Study:
- To evaluate the relationship between headache and chronic functional constipation in children aged 4-12 years.
- To determine if constipation is a risk factor for headache in pediatric populations.
Main Methods:
- A cross-sectional study involving 326 children in Shiraz, Iran.
- Diagnosis of constipation and headache utilized ROME III criteria and the International Headache Classification (ICHD-2), respectively.
- Children with constipation were recruited from a pediatric gastroenterology clinic, with a control group of healthy school children.
Main Results:
- Headache prevalence was significantly higher in constipated children (19.8%) compared to controls (5.6%), with an odds ratio of 4.192.
- This association was significant for non-migraine headaches and mild headache severity.
- Mild headaches were notably more prevalent in constipated children (14.9% vs. 1.4%).
Conclusions:
- A strong correlation exists between chronic functional constipation and headache in children.
- These comorbid conditions may be linked to emotional stress, depression, and anxiety.
- Findings suggest constipation as a potential contributing factor to headaches in children.
Background/Aims:
Constipation and headache are prevalent conditions among children worldwide. Previous studies have shown the relationship between upper gastrointestinal complaints and headache in children. However, the association with lower gastrointestinal complaints such as constipation has not been investigated until present. The aim of this study is to evaluate the relationship between headache and chronic functional constipation in children aged 4-12 years old.
Materials And Methods:
This cross-sectional study has evaluated the prevalence of headache in 326 children in Shiraz, Iran 2012. All the subjects and their parents were interviewed based on a structured questionnaire for the diagnosis of constipation and headache. Children with constipation were selected from the Pediatric Gastroenterology Clinic Affiliated to the Shiraz University of Medical Sciences. The control group was selected from healthy children attending Shiraz schools. Diagnosis of headache and constipation were made based on the second Edition of The International Headache Classification (ICHD-2) and ROME III criteria, respectively.
Results:
Headache prevalence among children with constipation was significantly higher (19.8%) than that of the control group (5.6%) [Odds ratio (OR) 4.192, p<0.001], which was significant only in the non-migraine headache subtypes (15.1% vs 2.8%, OR 25, p<0.002). Among the headache subtypes of different severity (mild, moderate, severe), only mild headache was significantly more prevalent in constipated children (14.9% vs. 1.4%, in the control group, respectively, p<0.001).
Conclusion:
This study revealed a strong correlation between headache and chronic functional constipation, which can result from the effect of these comorbid conditions with emotional stress, depression, and anxiety.
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