Prevention of excessive endothelin-1 release in sclerotherapy: in vitro and in vivo studies

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David M Duffy1

  • 1Department of Dermatology, University of Southern California, Los Angeles Torrance, California.

Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [Et Al.]
|November 25, 2014
PubMed
Abstract

No abstract available in PubMed .

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Endothelins (ETs) are potent vasoactive peptides critical in the human body's various physiological and pathological processes. One of the most promising therapeutic strategies for treating pulmonary arterial hypertension (PAH) involves counteracting the effects of these endothelins using a class of drugs known as endothelin receptor antagonists.
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