Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Cognitive Development During Adulthood

Cognitive Development During Adulthood

Cognitive development continues throughout adulthood, undergoing significant shifts across early, middle, and late stages. Individual transition occurs from adolescent idealism to pragmatic and adaptable thinking in early adulthood. During this period, individuals learn to integrate personal beliefs with the recognition that other perspectives are equally valid. Exposure to the complexities of modern society, diverse experiences, and higher education contribute to this adaptive thought process,...

Pharmacodynamics in Geriatric Patients: Effects of Age

Pharmacodynamics in Geriatric Patients: Effects of Age

Age-related pharmacokinetic changes are extensively documented, but understanding age-related pharmacodynamic alterations is relatively limited. This knowledge gap can be partly attributed to the complexity of developing appropriate measures of drug responses compared to bioanalytical methods for determining drug concentrations.Most information regarding age-related differences in human pharmacodynamics originates from cross-sectional studies. However, these studies assume that observed mean...

Cognitive Enhancers: Cholinesterase Inhibitors and NMDA Receptor Antagonists

Cognitive Enhancers: Cholinesterase Inhibitors and NMDA Receptor Antagonists

Cognitive enhancers, also known as "smart drugs," are substances used to enhance memory, mental alertness, and concentration. These can be natural or synthetic and improve cognition in conditions like Alzheimer's disease (AD) and other neurodegenerative diseases. Some common examples include caffeine, amphetamines, methylphenidate, modafinil, arecoline, donepezil, vortioxetine, and piracetam. These enhancers work on the principle of synaptic plasticity and altered circuit function.

The Effect of Aging on Tissues

The Effect of Aging on Tissues

Several body functions deteriorate with age. The external signs of aging are easily identifiable. For example, the skin becomes dry, less elastic, and thins out, forming wrinkles. The skin of the face begins to appear looser due to a decrease in the levels of elastic and collagen fibers in the connective tissue. Additionally, melanin production in the hair follicle decreases with age, resulting in gray hair. Moreover, the senses of sight and hearing decline, so glasses and hearing aids may...

Drug Dosing: Geriatric Patients

Drug Dosing: Geriatric Patients

Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...

Alzheimer's Disease: Treatment

Alzheimer's Disease: Treatment

Alzheimer's Disease (AD), a neurodegenerative disorder, is pathologically identified by amyloid plaques and neurofibrillary tangles composed of tau protein. AD pharmacotherapy aims to manage cognitive symptoms, delay disease progression, and treat behavioral symptoms. The treatment is primarily symptomatic and palliative, with no definitive disease-modifying therapy available. Cholinesterase inhibitors, including donepezil (Aricept), rivastigmine (Exelon), and galantamine (Razadyne), are...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Comparison of lung scintigraphy with multi-slice spiral computed tomography in the diagnosis of pulmonary embolism.

Clinical nuclear medicine·2009

Same author

[Analysis on the characters of injuries in body surface and deduction of injury-causing instruments in 146 cases].

Fa yi xue za zhi·2009

Same author

Impact of ketone and amino on the inner shell of guanine.

Journal of synchrotron radiation·2009

Same author

Actin turnover is required for myosin-dependent mitochondrial movements in Arabidopsis root hairs.

PloS one·2009

Same author

Direct observation of a widely tunable bandgap in bilayer graphene.

Nature·2009

Same author

Investigation of second-order nonlinearity in poled-polymer during photobleaching.

Optics express·2009

Search research articles

Related Experiment Video

Updated: Apr 20, 2026

Orienteering as a Tool for Cognitive Research: An Implementation Guide

Orienteering as a Tool for Cognitive Research: An Implementation Guide

Published on: November 29, 2024

Exercise improves cognitive function in aging patients.

Jian-Ping Hu¹, Yan-Hua Guo¹, Feng Wang¹

¹The Center of Physical Health, Henan Polytechnic University Jiaozuo 454000, Henan Province, P. R. China.

International Journal of Clinical and Experimental Medicine

|November 25, 2014

Summary

This summary is machine-generated.

Regular exercise significantly enhances cognitive function and daily living activities in older adults with mild cognitive impairment. This study demonstrates exercise

Keywords:

Aging cognitive function dementia exercise mild cognitive impairment

More Related Videos

Working Memory Training for Older Participants: A Control Group Training Regimen and Initial Intellectual Functioning Assessment

Working Memory Training for Older Participants: A Control Group Training Regimen and Initial Intellectual Functioning Assessment

Published on: September 20, 2020

Getting to Compliance in Forced Exercise in Rodents: A Critical Standard to Evaluate Exercise Impact in Aging-related Disorders and Disease

Getting to Compliance in Forced Exercise in Rodents: A Critical Standard to Evaluate Exercise Impact in Aging-related Disorders and Disease

Published on: August 22, 2014

Related Experiment Videos

Last Updated: Apr 20, 2026

Orienteering as a Tool for Cognitive Research: An Implementation Guide

Orienteering as a Tool for Cognitive Research: An Implementation Guide

Published on: November 29, 2024

Working Memory Training for Older Participants: A Control Group Training Regimen and Initial Intellectual Functioning Assessment

Working Memory Training for Older Participants: A Control Group Training Regimen and Initial Intellectual Functioning Assessment

Published on: September 20, 2020

Getting to Compliance in Forced Exercise in Rodents: A Critical Standard to Evaluate Exercise Impact in Aging-related Disorders and Disease

Getting to Compliance in Forced Exercise in Rodents: A Critical Standard to Evaluate Exercise Impact in Aging-related Disorders and Disease

Published on: August 22, 2014

Area of Science:

Gerontology
Neurology
Physical Therapy

Background:

Cognitive decline is prevalent in aging populations.
Mild cognitive impairment affects memory and daily functioning.
Exercise interventions are being explored for cognitive restoration.

Purpose of the Study:

To investigate the restorative effects of a six-month exercise program on cognitive function and physical abilities in older adults with mild cognitive impairment.
To compare outcomes between an exercise group and a control group.

Main Methods:

Ninety-six patients with mild cognitive impairment participated in a structured exercise program for six months.
Cognitive function was assessed using the Chinese Mini Mental Status Examination (MMSE).
Physical abilities were evaluated through Activity of Daily Living (ADL) assessments and body movement testing.

Main Results:

Exercise participants showed significant improvements in immediate memory (p < 0.001) and delayed recall (p = 0.004) compared to controls.
Improvements were also observed in activities of daily living (p < 0.001), body movement (p < 0.05), arm stability (p < 0.001), and rotation (p < 0.05).

Conclusions:

Participation in an exercise program can effectively improve cognitive function in older adults with mild cognitive impairment.
Exercise positively impacts physical abilities, including daily living activities and body movement capacity.
This study supports exercise as a beneficial intervention for managing cognitive decline in the elderly.