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Re-operation in pancreas transplantation.
C E Cornejo-Carrasco1, L Fernández-Cruz1
1Servicio de Cirugía Bilio-Pancreático, Hospital Clínic de Barcelona, Barcelona, Spain.
Transplantation Proceedings
|November 26, 2014
Summary
Re-operations after pancreas transplantation, often due to complications like bleeding or thrombosis, significantly reduce graft and patient survival rates. Early re-operation is more common and impactful than late re-operation.
Area of Science:
- Transplantation Surgery
- Surgical Complications
- Graft Survival
Background:
- Pancreas transplantation complications increase morbidity and graft loss.
- Re-operations are a significant concern in pancreas transplant outcomes.
Purpose of the Study:
- Determine the frequency of early and late re-operations in pancreas transplantation.
- Analyze the impact of re-operations on graft survival, patient survival, and hospital mortality.
Main Methods:
- Retrospective analysis of 238 pancreas transplants (2001-2011).
- Evaluation of surgical complications leading to early and late re-operations.
- Comparison of outcomes between re-operated and non-re-operated patients.
Main Results:
- 25.63% of patients (61/238) required re-operation, mostly early (58 patients).
- Common causes for re-operation included bleeding (8.8%) and pancreas graft thrombosis (6.3%).
- Graft survival at 1 and 5 years was significantly lower in re-operated patients (74% vs 98% and 57% vs 93%, respectively; P=.0001).
Conclusions:
- Surgical complications necessitating re-operations are linked to increased morbidity.
- Re-operations negatively impact both pancreas graft and patient survival rates.
