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Toxicity Testing in Animals

Toxicity Testing in Animals

Toxicity tests in animals are grounded on two main assumptions: first, the effects observed in laboratory animals can be extrapolated to humans, especially when adjusted for body surface area; second, high-dose exposure in animals is essential to identify potential human hazards from lower doses. This is based on the quantal dose-response concept, which faces the challenge of extrapolating results from relatively few test animals to much larger human populations. For example, a 0.01% incidence...

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Related Experiment Video

Updated: Apr 20, 2026

Ex vivo Mimicry of Normal and Abnormal Human Hematopoiesis

Ex vivo Mimicry of Normal and Abnormal Human Hematopoiesis

Published on: April 10, 2012

Exotic animal hematology

Terry W Campbell¹

¹Department of Clinical Sciences, College of Veterinary Medicine andBiomedical Sciences, Colorado State University, 300 West Drake Road, Fort Collins, CO 80523, USA.

The Veterinary Clinics of North America. Exotic Animal Practice

|November 26, 2014

Summary

No abstract available in PubMed .

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