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Related Concept Videos

Menopause01:28

Menopause

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Menopause, a natural biological process marking the end of a woman's fertility, typically occurs between the fifth and sixth decade of life. This phase is characterized by the exhaustion of the ovarian follicle pool, leading to less responsive ovaries despite the high levels of Follicle Stimulating Hormone (FSH) and Luteinizing Hormone (LH). The consequential decrease in estrogen production results in symptoms like hot flashes, heavy sweating, headaches, hair loss, muscle pains, vaginal...
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Bone Disorders01:29

Bone Disorders

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Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
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Bone Remodeling01:40

Bone Remodeling

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Bone remodeling is a continuous and balanced process of bone resorption by osteoclasts and bone formation by osteoblasts. In adults, it helps maintain bone mass and calcium homeostasis. While mechanical stress can stimulate turnover as part of the normal maintenance and reparative process, several hormones also regulate bone remodeling.
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Hormones and Bone Tissue01:17

Hormones and Bone Tissue

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The endocrine system produces and secretes hormones, which interact with the skeletal system. These hormones control bone growth, maintain bone once it is formed, and remodel it.
Hormones That Influence Osteoblasts and/or Maintain the Matrix
Several hormones are necessary for controlling bone growth and maintaining the bone matrix. The pituitary gland secretes growth hormone (GH), which, as its name implies, controls bone growth. This happens in several ways: first, it triggers chondrocyte...
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Essential Minerals for Bone Health01:31

Essential Minerals for Bone Health

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The minerals contained in all of the food we consume are essential for our organ systems. However, certain essential minerals, such as calcium, phosphorus, magnesium, manganese, and fluoride, largely affect bone health.
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Calcium is a critical component of bones, especially in the form of calcium phosphate and calcium carbonate. Since the body cannot make calcium, it must be obtained from the diet. However, calcium cannot be absorbed from the small intestine without...
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Study Designs in Epidemiology01:20

Study Designs in Epidemiology

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Epidemiological study designs are fundamental tools for investigating the distribution, determinants, and control of health conditions in populations. They help researchers understand the relationships between exposures and outcomes, and they broadly fall into two categories: "observational" and "experimental" studies.
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Related Experiment Video

Updated: Apr 20, 2026

Estrogen-Like Effect of Bazi Bushen Capsule in Ovariectomized Rats
08:56

Estrogen-Like Effect of Bazi Bushen Capsule in Ovariectomized Rats

Published on: April 7, 2023

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Postmenopausal hot flushes and bone mineral density: a longitudinal study.

Pauliina Tuomikoski1, Olavi Ylikorkala, Tomi S Mikkola

  • 1Department of Obstetrics and Gynecology, Helsinki University Central Hospital, Helsinki, Finland.

Acta Obstetricia Et Gynecologica Scandinavica
|November 26, 2014
PubMed
Summary

Menopausal hot flushes do not appear to impact bone mineral density in recently menopausal women. This observational study found no association between hot flush severity and bone density at baseline or over time.

Keywords:
DXAVasomotor symptomsdual-energy X-ray absorptiometrymenopauseosteoporosis

Related Experiment Videos

Last Updated: Apr 20, 2026

Estrogen-Like Effect of Bazi Bushen Capsule in Ovariectomized Rats
08:56

Estrogen-Like Effect of Bazi Bushen Capsule in Ovariectomized Rats

Published on: April 7, 2023

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Area of Science:

  • Reproductive Endocrinology
  • Bone Metabolism
  • Menopause Research

Background:

  • Hot flushes are a common symptom during menopause.
  • Bone mineral density (BMD) is a critical factor in assessing osteoporosis risk.
  • The relationship between menopausal hot flushes and BMD requires further investigation.

Purpose of the Study:

  • To investigate the potential association between the presence and severity of menopausal hot flushes and bone mineral density.
  • To determine if hot flushes predict changes in BMD over time in postmenopausal women.

Main Methods:

  • An observational study was conducted at a university clinic.
  • 143 healthy women, 6-36 months postmenopause, participated.
  • Bone mineral density was measured at baseline and approximately 6.2 years later; hot flushes were prospectively recorded.

Main Results:

  • No significant differences in lumbar or hip bone mineral density were observed between women with varying degrees of hot flushes at baseline.
  • Over the follow-up period, bone mineral density changes did not correlate with the initial hot flush status.
  • Lumbar bone mineral density decreased annually in non-hormone therapy users and increased in users.

Conclusions:

  • Menopausal hot flushes do not appear to be a determinant of bone mass density in recently menopausal women.
  • The severity of hot flushes at baseline does not predict future bone mineral density changes.
  • Further research may explore other factors influencing bone health during menopause.