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Gender differences in neurologic emergencies part I: a consensus summary and research agenda on cerebrovascular

Tracy E Madsen1, Todd A Seigel, Richard S Mackenzie

  • 1Department of Emergency Medicine, The Alpert Medical School of Brown University Rhode Island Hospital, Providence, RI.

Academic Emergency Medicine : Official Journal of the Society for Academic Emergency Medicine
|November 26, 2014
PubMed

Insights

Future research is needed to understand sex and gender differences in cerebrovascular emergencies like stroke and migraine. This will improve emergency department (ED) diagnosis, treatment, and patient outcomes.

Area of Science:

  • Neurology
  • Emergency Medicine
  • Neuroscience

Background:

  • Cerebrovascular neurologic emergencies are leading causes of death and disability.
  • Sex and gender differences in these conditions are increasingly recognized but not fully understood.
  • Emergency departments (EDs) are crucial for diagnosing and treating these emergencies.

Purpose of the Study:

  • To identify research gaps regarding sex and gender in neurologic emergencies.
  • To establish a future research agenda for emergency physicians.
  • To guide the incorporation of sex and gender considerations into ED research, evaluation, and management.

Main Methods:

  • A consensus conference working group utilized a standardized nominal group technique.
  • Existing literature gaps concerning sex and gender in neurologic emergencies were evaluated.
  • A research agenda was developed and approved by working group participants.

Main Results:

  • Specific research priorities were recommended for stroke, subarachnoid hemorrhage (SAH), and migraine.
  • The recommendations focus on the role of sex and gender in ED diagnosis, treatment, and outcomes.
  • Future research should investigate biologic and pathophysiologic differences between sexes.

Conclusions:

  • A clear research agenda is established to address sex and gender disparities in neurologic emergencies.
  • This agenda aims to improve the ED care of patients experiencing stroke, SAH, and migraine.
  • Further investigation into sex- and gender-based biological differences is essential for advancing patient care.

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