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Updated: Apr 20, 2026

Rapid Diagnosis of Avian Influenza Virus in Wild Birds: Use of a Portable rRT-PCR and Freeze-dried Reagents in the Field
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Rapid Diagnosis of Avian Influenza Virus in Wild Birds: Use of a Portable rRT-PCR and Freeze-dried Reagents in the Field

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Human infection with influenza virus A(H10N8) from live poultry markets, China, 2014

Tao Zhang, Yuhai Bi, Huaiyu Tian

    Emerging Infectious Diseases
    |November 27, 2014
    PubMed

    Insights

    Avian influenza A(H10N8) virus infections in humans were first seen in China in 2013. Genetic analysis indicates these human H10N8 strains likely originated from poultry in live-bird markets visited by infected individuals.

    Area of Science:

    • Virology
    • Infectious Diseases
    • Public Health

    Background:

    • The first human infection with avian influenza A(H10N8) virus was reported in China in December 2013.
    • Understanding the origin and transmission of novel influenza strains is crucial for public health preparedness.

    Purpose of the Study:

    • To characterize the genetic makeup and features of the avian influenza A(H10N8) virus from a human case.
    • To investigate the potential source of the human A(H10N8) infection by examining viruses from local live poultry markets.

    Main Methods:

    • Genome sequencing of avian influenza A(H10N8) virus isolates from a human patient.
    • Virus characterization of strains obtained from poultry in live markets frequented by the infected individual.
    • Comparative genomic analysis to determine viral origins.

    Main Results:

    • The characterized H10N8 virus strains from the human patient and poultry shared significant genetic similarities.
    • Genomic sequencing data strongly suggested a common origin for the human and poultry isolates.
    • Evidence points towards live poultry markets as the likely source of human A(H10N8) infection.

    Conclusions:

    • The findings indicate that live poultry markets served as the origin for the human A(H10N8) influenza virus infections.
    • This highlights the importance of surveillance in live-bird markets for preventing zoonotic transmission of avian influenza.

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