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Metastatic malignancy associated with reflex sympathetic dystrophy.

R Ameratunga1, M Daly, D E Caughey

  • 1Rheumatology Department, Auckland Hospital, New Zealand.

The Journal of Rheumatology
|March 1, 1989
PubMed
Summary
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Reflex sympathetic dystrophy of the foot was diagnosed in a patient. Postmortem examination revealed the cause to be metastatic lung carcinoma, highlighting a rare presentation of advanced cancer.

Area of Science:

  • Oncology
  • Neurology
  • Pathology

Background:

  • Reflex sympathetic dystrophy (RSD), also known as complex regional pain syndrome (CRPS), is a chronic pain condition.
  • It typically affects an extremity, often following an injury.
  • RSD of the foot is a recognized clinical presentation.

Observation:

  • A patient presented with symptoms consistent with reflex sympathetic dystrophy localized to the foot.
  • Initial clinical presentation mimicked a primary neurological or musculoskeletal condition.
  • Diagnostic imaging and biopsy were pursued for definitive diagnosis.

Findings:

  • Biopsy of the small bones of the foot confirmed the presence of metastatic cancer.
  • Subsequent postmortem examination identified the primary tumor as carcinoma of the lung.

Related Experiment Videos

  • This case highlights an unusual metastatic pattern of lung cancer.

    • Implications:

    • Metastatic lung carcinoma can present with rare and atypical symptoms, such as reflex sympathetic dystrophy.
    • Early recognition of unusual presentations is crucial for timely diagnosis and management of advanced malignancies.
    • This case underscores the importance of thorough investigation in patients with seemingly localized pain syndromes.