Related Experiment Video

Updated: Apr 20, 2026

Use of Rabbit Eyes in Pharmacokinetic Studies of Intraocular Drugs
10:02

Use of Rabbit Eyes in Pharmacokinetic Studies of Intraocular Drugs

Published on: July 23, 2016

33.8K

Ophthalmic patients on antithrombotic drugs: a review and guide to perioperative management

K-L Kong1, J Khan2

  • 1Department of Anaesthesia, SWBH NHS Trust, Birmingham, UK.

The British Journal of Ophthalmology
|November 27, 2014
PubMed

Insights

Managing patients on antiplatelet and anticoagulant drugs undergoing eye surgery is crucial. This review guides optimal drug management to minimize bleeding and clotting risks in ophthalmic procedures.

Area of Science:

  • Ophthalmology
  • Pharmacology
  • Surgical Science

Background:

  • Increasing prevalence of antiplatelet and anticoagulant drug use in patients undergoing ophthalmic surgery.
  • Growing risk of bleeding complications in this patient population.

Purpose of the Study:

  • To review traditional and newer antiplatelet and anticoagulant agents.
  • To provide recommendations for managing these medications in ophthalmic surgery.
  • To minimize bleeding and thrombotic risks.

Main Methods:

  • Literature review of antiplatelet and anticoagulant agents.
  • Analysis of drug use in cataract, vitreoretinal, glaucoma, and oculoplastic surgery.
  • Development of management guidelines.

Main Results:

  • Identification of specific risks associated with various agents.
  • Recommendations for continuation, cessation, and re-commencement of medications.
  • Strategies to balance bleeding and thrombotic risks.

Conclusions:

  • Optimal management of antiplatelet and anticoagulant drugs is essential for patient safety in ophthalmic surgery.
  • Evidence-based recommendations aid in minimizing perioperative complications.
  • Awareness of drug profiles is key for successful surgical outcomes.

Keywords:
DrugsGlaucomaPharmacologyPosterior ChamberTreatment Surgery

More Related Videos

Ocular Therapeutic Delivery and Advanced Tissue Retrieval in Adult Rats06:30

Ocular Therapeutic Delivery and Advanced Tissue Retrieval in Adult Rats

Published on: May 23, 2025

1.2K
Subretinal Implantation of RPE on a Carrier in Minipigs: Guidelines for Preoperative Preparations, Surgical Techniques, and Postoperative Care11:06

Subretinal Implantation of RPE on a Carrier in Minipigs: Guidelines for Preoperative Preparations, Surgical Techniques, and Postoperative Care

Published on: November 11, 2022

3.5K

Related Concept Videos

Venous Thrombosis III: Interprofessional Care01:29

Venous Thrombosis III: Interprofessional Care

Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
477
Aneurysm IV: Nursing Management01:22

Aneurysm IV: Nursing Management

Vigilant monitoring for aneurysm rupture is essential for patients undergoing aortic surgery.Preoperative Nursing ManagementContinuously monitor the patient for manifestations of aneurysm rupture, such as pallor, weakness, tachycardia, hypotension, abdominal, back, groin, or periumbilical pain, changes in consciousness, and a pulsating abdominal mass. Regularly assess the patient's peripheral pulses.Instruct the patient to consume a clear liquid diet the day before surgery and administer...
610
Venous Thrombosis IV: Nursing Management01:30

Venous Thrombosis IV: Nursing Management

Nursing management begins with a thorough assessment of the patient's health history. Key factors include trauma to veins, peripherally inserted central catheters, varicose veins, recent pregnancy or childbirth, surgery, bacteremia, prolonged bed rest, atrial fibrillation, COPD, heart failure, cancer, coagulation disorders, myocardial infarction, spinal cord injury, stroke, prolonged travel, recent bone fractures, and dehydration. Review medication intake, particularly oral contraceptives,...
400
Peripheral Artery Disease V: Postoperative Nursing Management01:23

Peripheral Artery Disease V: Postoperative Nursing Management

During the postoperative period, it is crucial to focus on maintaining circulation, identifying and managing potential complications, and planning for discharge.Nursing AssessmentVital signs monitoring: Regularly monitor vital signs, including blood pressure, heart rate, respiratory rate, and temperature, to detect early signs of complications such as bleeding and infection.Circulation assessment: Monitor pulses, perform Doppler assessments, and check capillary refill, color, temperature, and...
610
Cardiomyopathy VII: Pre and Post Operative Nursing Management01:28

Cardiomyopathy VII: Pre and Post Operative Nursing Management

Patients with hypertrophic cardiomyopathy (HCM) and left ventricular outflow tract (LVOT) obstruction who remain symptomatic despite optimal medical therapy may undergo a septal myectomy (Morrow procedure). This procedure involves excising a portion of the hypertrophied septum below the aortic valve using a heart-lung machine to improve blood flow through the LVOT. Effective preoperative and postoperative nursing management ensures successful patient outcomes, minimizes complications, and...
442
Ophthalmic Drug Delivery Systems01:23

Ophthalmic Drug Delivery Systems

Ophthalmic drug delivery faces major limitations due to poor absorption across the corneal membrane. This process is primarily driven by diffusion and is influenced by two main factors: the physicochemical properties of the drug and tear drainage. Most ophthalmic drugs, such as pilocarpine, epinephrine, atropine, and local anesthetics, are weak bases. They are typically formulated at an acidic pH to enhance chemical stability. However, this leads to high ionization, reducing their ability to...
256