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Intranasal Immunization and Milk Collection in Studies of Maternal Immunization in New Zealand White Rabbits Oryctolagus cuniculus
Published on: July 31, 2021
Maternal immunization: opportunities for scientific advancement.
Richard H Beigi1, Kimberly B Fortner2, Flor M Munoz3
1Department of Obstetrics, Gynecology and Reproductive Sciences, Magee-Womens Hospital of the University of Pittsburgh Medical Center, Pennsylvania.
Maternal immunization offers a promising strategy to protect pregnant women and infants from infectious diseases. This approach, building on successes like tetanus vaccines, aims to prevent illnesses such as influenza and pertussis.
Area of Science:
- Immunology
- Infectious Diseases
- Vaccinology
Background:
- Maternal immunization is a proven strategy for preventing infectious diseases in pregnant women and infants.
- Successes include vaccines for maternal and neonatal tetanus, leading to broader acceptance for other diseases.
- Influenza and pertussis are key examples of vaccine-preventable diseases impacting pregnant populations.
Purpose of the Study:
- To foster progress in the clinical development of vaccines for use during pregnancy.
- To identify barriers and opportunities for scientific advancement in maternal immunization.
- To reduce the burden of infectious conditions with perinatal significance.
Main Methods:
- Convening a multidisciplinary group of stakeholders.
- Holding meetings sponsored by the Division of Microbiology and Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health (NIH).
- Focusing on the development of vaccines against relevant pathogens for perinatal use.
Main Results:
- Identified potential barriers to maternal immunization.
- Highlighted opportunities for scientific advancement in the field.
- Established a collaborative platform for vaccine development.
Conclusions:
- Maternal immunization is a critical strategy for protecting maternal and infant health.
- Further research and development are needed to overcome barriers and expand vaccine use in pregnancy.
- Continued collaboration among stakeholders is essential for advancing maternal immunization programs.
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