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Published on: June 29, 2013
Tuberous sclerosis and cardiac tumors: new electrocardiographic finding in an infant
Insights
Cardiac rhabdomyomas, common in children with tuberous sclerosis, can cause ECG abnormalities. This case highlights a unique T-wave finding in an infant with tuberous sclerosis and cardiac rhabdomyomas, previously undescribed in this patient population.
Area of Science:
- Pediatric Cardiology
- Oncology
- Genetics
Background:
- Cardiac rhabdomyoma is the most common primary cardiac tumor in children.
- It is frequently associated with tuberous sclerosis complex (TSC).
- While often asymptomatic, cardiac rhabdomyomas can manifest with various electrocardiographic (ECG) abnormalities.
Abstract:
Cardiac rhabdomyoma, the primary cardiac tumor most often diagnosed in children, is frequently present in patients with tuberous sclerosis. Most pediatric patients with rhabdomyoma are asymptomatic; however, various electrocardiographic abnormalities can be detected, such as Wolff-Parkinson-White syndrome, ectopic atrial tachycardia, and atrioventricular node dysfunction. We describe the case of a 10-month-old infant girl who had tuberous sclerosis and multiple cardiac rhabdomyomas. Her electrocardiographic presentation was notable for dome-shaped T waves and no ST segment in some leads. To our knowledge, this electrocardiographic finding has not been described in patients with tuberous sclerosis and cardiac masses.
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