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Updated: Apr 20, 2026

Multidisciplinary Approach to Obesity Management: A Case Report
Published on: May 30, 2025
Weight loss maintenance for 2 years after a 6-month randomised controlled trial comparing education-only and
Yoshio Nakata1, Masafumi Okada, Koichi Hashimoto
1Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.
Objective:
Our previous study, a 6-month randomised controlled trial, demonstrated that a group-based support promoted weight loss as compared to an education-only intervention. The purpose of this study was to examine weight loss maintenance for 2 years.
Methods:
Originally, 188 overweight Japanese adults, aged 40-65 years, were randomly assigned to 3 groups: control, education-only or group-based support. After the 6-month intervention, 125 participants in the education-only and the group-based support groups were followed up for 2 years. The primary outcome was the amount of weight lost. The participants were retrospectively grouped into quartiles of percent weight loss for secondary analyses.
Results:
At the end of follow-up, the amount of weight lost in the education-only and the group-based support groups was the same (3.3 kg). Secondary analyses using data of those who completed the study (n = 100) revealed that the participants in the highest quartile of percent weight loss significantly increased their step counts and moderate-to-vigorous physical activity compared with the lowest quartile. No significant differences were observed in the energy intake among the four groups.
Conclusion:
The effects of group-based support disappear within 2 years. Increasing physical activity may be a crucial factor for successful maintenance of weight loss.
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