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An update on the use of immunoglobulin for the treatment of immunodeficiency disorders

Stephanie Albin1, Charlotte Cunningham-Rundles

  • 1Division of Allergy & Clinical Immunology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.

Immunotherapy
|November 28, 2014
PubMed

For patients with significant antibody deficiencies, immunoglobulin therapy is the mainstay of treatment as it significantly reduces both the frequency and severity of infections. The formulations and delivery methods of immunoglobulin have evolved over time, and continued improvements have allowed for increased access to this effective medication. This review is an update on the current status of immunoglobulin therapy in immunodeficiency disorders, and discusses the mechanisms, forms and dosing, and indications for immunoglobulin replacement.

Keywords:
antibody deficiencyimmunoglobulin replacementintravenous immunoglobulinmechanisms of immunoglobulinprimary immunodeficiencysubcutaneous immunoglobulin

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