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Related Concept Videos

Knee Joint01:23

Knee Joint

3.8K
The knee joint is the most complicated joint in the body. It consists of three articulations– two tibiofemoral and one patellofemoral. As is characteristic of synovial joints, the knee joint has a thin articular capsule that partially surrounds this joint cavity. Additionally, several ligaments, muscles, and cartilaginous structures support the movement of the knee.
A total of seven ligaments support the knee joint. The patellar ligament, which is also attached to the quadriceps femoris...
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Related Experiment Video

Updated: Apr 20, 2026

Anterior Cruciate Ligament Transection and Synovial Fluid Lavage in a Rodent Model to Study Joint Inflammation and Posttraumatic Osteoarthritis
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Optimized cartilage visualization using 7-T sodium ((23)Na) imaging after patella dislocation.

Harald K Widhalm1, Sebastian Apprich2, Goetz H Welsch2,3

  • 1Department of Traumatology, Center for Joints and Cartilage, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria. harald.widhalm@meduniwien.ac.at.

Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA
|November 29, 2014
PubMed
Summary
This summary is machine-generated.

This study utilized 7-Tesla sodium MRI to assess knee cartilage after patella dislocation. Sodium MRI can detect early cartilage changes, aiding timely treatment and preventing further damage.

Keywords:
7 TCartilageGlycosaminoglycansMagnetic resonance imagingPatella dislocationSodium

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Area of Science:

  • Orthopedics
  • Radiology
  • Biomedical Engineering

Background:

  • Recurrent patella dislocation frequently causes retropatellar cartilage damage.
  • Current diagnostic methods may cause patient discomfort and prolong care.
  • There is a need for improved imaging techniques for early detection of cartilage lesions.

Purpose of the Study:

  • To develop a detailed method for examining patellar cartilage tissue using 7-Tesla sodium MRI.
  • To reduce patient discomfort and time of care in diagnosing cartilage lesions.
  • To compare sodium MRI findings in patients with patella dislocation to healthy volunteers.

Main Methods:

  • Nine patients with recent patella dislocation underwent 7-Tesla MRI of the knee.
  • Axial sodium ((23)Na) images were acquired using a 3D GRE sequence.
  • Morphological cartilage grading and sodium signal-to-noise ratio (SNR) were calculated and compared between patients and volunteers.

Main Results:

  • Two patients had ICRS grade 3 defects, three had grade 2, and three had grade 1.
  • Mean sodium SNR in cartilage was comparable between patients (13.4 ± 2.5) and volunteers (14.6 ± 3.7).
  • A significant negative correlation was found between age and sodium SNR in the medial facet (p=0.030).
  • Sodium SNR decreased significantly with increasing cartilage lesion grade (p < 0.001).

Conclusions:

  • 7-Tesla sodium MRI enables earlier detection of patellar cartilage alterations post-dislocation.
  • This advanced imaging can facilitate prompt therapeutic interventions.
  • Early diagnosis and treatment can help prevent secondary conditions during rehabilitation.