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Updated: Apr 20, 2026

Lung Rapid Recovery Procurement Combined with Abdominal Normothermic Regional Perfusion in Controlled Donation after Circulatory Death
Published on: August 15, 2022
ECMO as bridge to lung transplant.
Mauer Biscotti1, Joshua Sonett1, Matthew Bacchetta1
1Section of Thoracic Surgery, Price Family Center for Comprehensive Chest Care, Center for Acute Respiratory Care, Columbia University Medical Center, New York-Presbyterian Hospital, 161 Fort Washington Avenue, 3rd Floor, New York, NY 10032, USA.
Extracorporeal membrane oxygenation (ECMO) effectively bridges critically ill patients to lung transplantation when combined with rigorous clinical assessment. Postoperative survival is acceptable for successfully transplanted patients, but further research is needed.
Area of Science:
- Cardiology
- Pulmonary Medicine
- Transplant Surgery
Background:
- Lung transplantation has advanced significantly over 50 years.
- Extracorporeal membrane oxygenation (ECMO) is increasingly utilized for critical care.
- ECMO serves as a bridge to lung transplantation (BTT) for select patients.
Purpose of the Study:
- To highlight the successful application of ECMO as a bridge to lung transplantation (BTT).
- To emphasize the importance of stringent daily clinical assessment in managing BTT patients.
- To evaluate postoperative survival rates in patients bridged to lung transplantation with ECMO.
Main Methods:
- Retrospective analysis of critically ill patients undergoing ECMO as a bridge to lung transplantation.
- Application of stringent daily clinical assessments to determine ongoing transplant eligibility.
- Monitoring of postoperative survival rates following successful lung transplantation.
Main Results:
- ECMO successfully bridged critically ill patients to lung transplantation.
- Patients who met transplant criteria and underwent transplantation demonstrated acceptable postoperative survival rates.
- Rigorous daily clinical assessment was key to managing patients on ECMO BTT.
Conclusions:
- ECMO is a viable strategy for bridging critically ill patients to lung transplantation.
- Stringent clinical assessment is crucial for optimizing outcomes in ECMO BTT patients.
- Larger studies are required to refine decision-making algorithms and improve outcomes for BTT patients.
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