Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Skeletal Muscle Anatomy00:55

Skeletal Muscle Anatomy

96.2K
Skeletal muscle is the most abundant type of muscle in the body. Tendons are the connective tissue that attaches skeletal muscle to bones. Skeletal muscles pull on tendons, which in turn pull on bones to carry out voluntary movements.
96.2K
Bioreactor Design and Operational System01:29

Bioreactor Design and Operational System

169
Bioreactors are engineered vessels designed to cultivate microorganisms under controlled conditions for industrial bioprocessing. They maintain sterility and allow precise regulation of pH, temperature, oxygen, and nutrient levels to optimize microbial growth and metabolite production. Bioreactors range from small laboratory units of 1 liter to industrial systems holding up to 500,000 liters, though only about 75% of their volume is actively used for fermentation. The remaining headspace...
169
Classification of Skeletal Muscle Fibers01:48

Classification of Skeletal Muscle Fibers

60.5K
Skeletal muscles continuously produce ATP to provide the energy that enables muscle contractions. Skeletal muscle fibers can be categorized into three types based on differences in their contraction speed and how they produce ATP, as well as physical differences related to these factors. Most human muscles contain all three muscle fiber types, albeit in varying proportions.
Slow-Twitch Muscle Fibers
Slow oxidative, muscle fibers appear red due to large numbers of capillaries and high levels of...
60.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Tenacibaculum xiamenense sp. nov., an algicidal bacterium isolated from coastal seawater.

International journal of systematic and evolutionary microbiology·2013
Same author

The anchoring protein SAP97 influences the trafficking and localisation of multiple membrane channels.

Biochimica et biophysica acta·2013
Same author

Aegilops tauschii draft genome sequence reveals a gene repertoire for wheat adaptation.

Nature·2013
Same author

Draft genome of the wheat A-genome progenitor Triticum urartu.

Nature·2013
Same author

Citreoviridin enhances tumor necrosis factor-α-induced adhesion of human umbilical vein endothelial cells.

Toxicology and industrial health·2013
Same author

Th17/Treg imbalance induced by increased incidence of atherosclerosis in patients with systemic lupus erythematosus (SLE).

Clinical rheumatology·2013

Related Experiment Video

Updated: Apr 20, 2026

Engineering Skeletal Muscle Tissues from Murine Myoblast Progenitor Cells and Application of Electrical Stimulation
08:38

Engineering Skeletal Muscle Tissues from Murine Myoblast Progenitor Cells and Application of Electrical Stimulation

Published on: March 19, 2013

21.8K

Engineering skeletal muscle tissue in bioreactor systems.

Yang An1, Dong Li1

  • 1Department of Plastic Surgery, Peking University Third Hospital, Beijing 100191, China.

Chinese Medical Journal
|November 29, 2014
PubMed
Summary
This summary is machine-generated.

Tissue engineering (TE) for skeletal muscle shows promise but faces challenges. Vascularization and bioreactor environments are crucial for developing functional engineered muscle tissue.

More Related Videos

Preclinical Drug Testing in Scalable 3D Engineered Muscle Tissues
08:07

Preclinical Drug Testing in Scalable 3D Engineered Muscle Tissues

Published on: April 7, 2023

4.7K
Assessing Functional Metrics of Skeletal Muscle Health in Human Skeletal Muscle Microtissues
09:30

Assessing Functional Metrics of Skeletal Muscle Health in Human Skeletal Muscle Microtissues

Published on: February 18, 2021

4.9K

Related Experiment Videos

Last Updated: Apr 20, 2026

Engineering Skeletal Muscle Tissues from Murine Myoblast Progenitor Cells and Application of Electrical Stimulation
08:38

Engineering Skeletal Muscle Tissues from Murine Myoblast Progenitor Cells and Application of Electrical Stimulation

Published on: March 19, 2013

21.8K
Preclinical Drug Testing in Scalable 3D Engineered Muscle Tissues
08:07

Preclinical Drug Testing in Scalable 3D Engineered Muscle Tissues

Published on: April 7, 2023

4.7K
Assessing Functional Metrics of Skeletal Muscle Health in Human Skeletal Muscle Microtissues
09:30

Assessing Functional Metrics of Skeletal Muscle Health in Human Skeletal Muscle Microtissues

Published on: February 18, 2021

4.9K

Area of Science:

  • Biomedical Engineering
  • Regenerative Medicine
  • Tissue Engineering

Background:

  • Skeletal muscle tissue engineering (TE) aims to reconstruct skeletal muscle loss.
  • Current TE approaches show limited success due to challenges in vascularization and innervation.
  • Engineered muscle constructs require integration with vascular and neural systems for viability and function.

Purpose of the Study:

  • To review the current state of the art in skeletal muscle tissue engineering.
  • To examine the role of bioreactor environments in skeletal muscle TE.
  • To identify key factors for successful engineered muscle development.

Main Methods:

  • Literature review of published articles and guidelines.
  • Selection of 106 relevant articles authored by recognized scientists in the field.
  • Analysis of current research on skeletal muscle TE and bioreactor applications.

Main Results:

  • Skeletal muscle TE is a promising field with significant medical potential.
  • Successful engineered muscle requires vascular system integration for nutrient and waste transport.
  • Functional constructs depend on neuromuscular junctions and mimicry of the in vivo environment via bioreactors.

Conclusions:

  • Vascularization is essential for engineered muscle development and maintenance.
  • Bioreactor environments are necessary to provide adequate stimuli and circulation.
  • Both vascular systems and bioreactors are critical for creating clinically applicable engineered muscle.