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Updated: Apr 20, 2026
A Sensitive Visual Method for the Detection of Hydrogen Sulfide Producing Bacteria
Published on: June 27, 2022
A High-Sensitivity Coumarin-Based Fluorescent Probe for Monitoring Hydrogen Sulfide in Living Cells
Qianqian Qiu1, Xin Deng1, Lei Jiao1
1Center of Drug Discovery, State Key Laboratory of Natural Medicines, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing, 210009, China.
Abstract:
A novel coumarin-based fluorescence probe has been constructed for the selective and sensitive detection of hydrogen sulfide (H2 S). This probe displays high sensitivity and linearity to H2 S in degassed PBS buffers and fetal bovine serum. It reacts with H2 S with high selectivity over Cys, GSH, and other anions. Meanwhile, successful detection of H2 S in living cells was also demonstrated.
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