Primary cardiac burkitt lymphoma presenting with abdominal pain
Dimitrios Tzachanis1, Rajan Dewar2, Katarina Luptakova2
1Cedars-Sinai Medical Center, 8700 Beverly Boulevard, AC1046-A, Los Angeles, CA 90048, USA.
Abstract:
We describe the case of a 44-year-old woman with primary Burkitt lymphoma of the heart who presented with abdominal bloating and epigastric discomfort secondary to tamponade physiology caused by a large pericardial effusion. The pericardial fluid contained a large number of highly atypical lymphocytes with moderate basophilic cytoplasm, rare punched-out vacuoles, a vesicular nuclear chromatin, large nucleolus, and marginated chromatin that by FISH were positive for the 8;14 translocation. She had no other sites of disease. She was treated with four alternating cycles of modified CODOX-M and IVAC in combination with rituximab and remains in remission more than 5 years since diagnosis.
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